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. 1978 Apr;62(4):475–479. doi: 10.1111/j.1476-5381.1978.tb07750.x

[3H]-Ouabain binding to peripheral organs of cats: effect of ethanol.

S P Banerjee, V K Sharma
PMCID: PMC1668040  PMID: 148933

Abstract

1 The specific [3H]-ouabain binding to microsomal fractions derived from cat heart, liver, spleen, and kidney increased significantly following chronic administration of ethanol. 2 Since ouabain binds exclusively to cell membrane (Na+ + K+)-adenosine triphosphatase ((Na+ + K+)-ATPase), these results provide evidence for an increase in number of (Na+ + K+)-ATPase macromolecules during chronic alcoholism. 3 The importance of the increase in number of (Na+ + K+)-ATPase molecules in the adaptive increase in ethanol metabolism and cardiac myopathy in chronic alcoholism is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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