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. 1978 Oct;64(2):305–309. doi: 10.1111/j.1476-5381.1978.tb17305.x

Changes in plasma noradrenaline concentration as a measure of release rate.

C R Benedict, M Fillenz, C Stanford
PMCID: PMC1668310  PMID: 709000

Abstract

1 A method is described for repeated sampling of plasma noradrenaline (NA) in freely moving rats. Na concentration does not change during the day or after adrenalectomy. 2 Exogenous NA has a half-life of 1.5 min; drugs which block neuronal and extra-neuronal uptake lengthen this to 6.3 min. 3 Swim-stress leads to a steep rise followed by a rapid decline in plasma NA concentration. 4 This method of plasma NA sampling can serve as a measure of both steady and rapid changes in release rate over long periods of time.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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