Abstract
1. The times of appearance and the concentrations of noradrenaline and adrenaline were determined fluorimetrically in the gut of the embryonic and developing chick. 2. In the duodenum and jejunum, noradrenaline was detected in embryos on the 12th day of incubation. The concentration continued to increase throughout the embryonic stage and attained a maximum within 3 days of hatching. Afterwards, it decreased to about one-third of the peak level. No adrenaline was detectable in most stages of development. 3. In the rectum, noradrenaline was detected in embryos on the 12th day of incubation; both noradrenaline and adrenaline were invariably found on the 15th day of incubation. The concentrations of both amines fluctuated after hatching, but the amount of adrenaline was always approximately 40% of the amount of noradrenaline, except in the adult.
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- ANTON A. H., SAYRE D. F. A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines. J Pharmacol Exp Ther. 1962 Dec;138:360–375. [PubMed] [Google Scholar]
- ANTON A. H., SAYRE D. F. THE DISTRIBUTION OF DOPAMINE AND DOPA IN VARIOUS ANIMALS AND A METHOD FOR THEIR DETERMINATION IN DIVERSE BIOLOGICAL MATERIAL. J Pharmacol Exp Ther. 1964 Sep;145:326–336. [PubMed] [Google Scholar]
- Bennett T., Cobb J. L. Studies on the avian gizzard: the development of the gizzard and its innervation. Z Zellforsch Mikrosk Anat. 1969;98(4):599–621. doi: 10.1007/BF00347035. [DOI] [PubMed] [Google Scholar]
- Bennett T., Malmfors T. The adrenergic nervous system of the domestic fowl (Gallus domesticus [L.]). Z Zellforsch Mikrosk Anat. 1970;106(1):22–50. doi: 10.1007/BF01027715. [DOI] [PubMed] [Google Scholar]
- CHANG C. C. A SENSITIVE METHOD FOR SPECTROPHOTOFLUOROMETRIC ASSAY OF CATECHOLAMINES. Int J Neuropharmacol. 1964 Dec;3:643–649. doi: 10.1016/0028-3908(64)90089-9. [DOI] [PubMed] [Google Scholar]
- DeSantis V. P., Långsfeld W., Lindmar R., Loffelholz K. Evidence for noradrenaline and adrenaline as sympathetic transmitters in the chicken. Br J Pharmacol. 1975 Nov;55(3):343–350. doi: 10.1111/j.1476-5381.1975.tb06937.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ENEMAR A., FALCK B. OBSERVATIONS ON THE APPEARANCE OF NOREPINEPHRINE IN THE SYMPATHETIC NERVOUS SYSTEM OF THE CHICK EMBRYO. Dev Biol. 1965 Apr;11:268–283. doi: 10.1016/0012-1606(65)90060-6. [DOI] [PubMed] [Google Scholar]
- Ignarro L. J., Shideman F. E. Appearance and concentrations of catecholamines and their biosynthesis in the embryonic and developing chick. J Pharmacol Exp Ther. 1968 Jan;159(1):38–48. [PubMed] [Google Scholar]
- Iversen L. L., De Champlain J., Glowinski J., Axelrod J. Uptake, storage and metabolism of norepinephrine in tissues of the developing rat. J Pharmacol Exp Ther. 1967 Sep;157(3):509–516. [PubMed] [Google Scholar]
- LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
- Pappano A. J., Löffelholz K. Ontogenesis of adrenergic and cholinergic neuroeffector transmission in chick embryo heart. J Pharmacol Exp Ther. 1974 Dec;191(3):468–478. [PubMed] [Google Scholar]
- Takewaki T., Ohashi H., Okada T. Non-cholinergic and non-adrenergic mechanisms in the contraction and relaxation of the chicken rectum. Jpn J Pharmacol. 1977 Feb;27(1):105–115. doi: 10.1254/jjp.27.105. [DOI] [PubMed] [Google Scholar]