Skip to main content
NCBI home page
The BMJ logoLink to The BMJ
. 1991 Mar 2;302(6775):496–499. doi: 10.1136/bmj.302.6775.496

Risk of tuberculosis in patients with HIV-I and HIV-II infections in Abidjan, Ivory Coast.

K M De Cock 1, E Gnaore 1, G Adjorlolo 1, M M Braun 1, M F Lafontaine 1, G Yesso 1, G Bretton 1, I M Coulibaly 1, G M Gershy-Damet 1, R Bretton 1, et al.
PMCID: PMC1669628  PMID: 1849431

Abstract

OBJECTIVE--To examine the association between HIV-II infection and tuberculosis. DESIGN--Cross sectional study comparing the prevalence of HIV-I and HIV-II infections in patients with tuberculosis and in blood donors. SETTING--Abidjan, Ivory Coast, west Africa. PATIENTS--2043 consecutive ambulant patients with tuberculosis (confirmed pulmonary, presumed pulmonary, or extrapulmonary) and 2127 volunteer blood donors. MAIN OUTCOME MEASURE--Prevalence of HIV-I and HIV-II infections as assessed by presence of serum antibodies. RESULTS--Overall rates of HIV infection were 40.2% in patients with tuberculosis (26.4% positive for HIV-I, 4.7% for HIV-II, and 9.0% for both); and 10.4% in blood donors (7.2% positive for HIV-I, 1.9% for HIV-II, and 1.3% for both). HIV-II infection was significantly more common in patients with all types of tuberculosis than in blood donors (97/2043, 4.7% v 40/2127, 1.9%; odds ratio 3.8%, 95% confidence interval 2.6 to 5.6). CONCLUSION--Both HIV-I and HIV-II infections are associated with tuberculosis in Abidjan. 35% of adult tuberculosis in Abidjan is attributable to HIV infection and 4% specifically to HIV-II.

Full text

PDF
496

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Colebunders R., Mann J. M., Francis H., Bila K., Izaley L., Kakonde N., Kabasele K., Ifoto L., Nzilambi N., Quinn T. C. Evaluation of a clinical case-definition of acquired immunodeficiency syndrome in Africa. Lancet. 1987 Feb 28;1(8531):492–494. doi: 10.1016/s0140-6736(87)92099-x. [DOI] [PubMed] [Google Scholar]
  2. De Cock K. M., Odehouri K., Colebunders R. L., Adjorlolo G., Lafontaine M. F., Porter A., Gnaore E., Diaby L., Moreau J., Heyward W. L. A comparison of HIV-1 and HIV-2 infections in hospitalized patients in Abidjan, Côte d'Ivoire. AIDS. 1990 May;4(5):443–448. doi: 10.1097/00002030-199005000-00010. [DOI] [PubMed] [Google Scholar]
  3. De Cock K. M., Porter A., Odehouri K., Barrere B., Moreau J., Diaby L., Kouadio J. C., Heyward W. L. Rapid emergence of AIDS in Abidjan, Ivory Coast. Lancet. 1989 Aug 19;2(8660):408–411. doi: 10.1016/s0140-6736(89)90590-4. [DOI] [PubMed] [Google Scholar]
  4. Harries A. D. Tuberculosis and human immunodeficiency virus infection in developing countries. Lancet. 1990 Feb 17;335(8686):387–390. doi: 10.1016/0140-6736(90)90216-r. [DOI] [PubMed] [Google Scholar]
  5. Kanki P. J., M'Boup S., Ricard D., Barin F., Denis F., Boye C., Sangare L., Travers K., Albaum M., Marlink R. Human T-lymphotropic virus type 4 and the human immunodeficiency virus in West Africa. Science. 1987 May 15;236(4803):827–831. doi: 10.1126/science.3033826. [DOI] [PubMed] [Google Scholar]
  6. Kanki P. J. West African human retroviruses related to STLV-III. AIDS. 1987 Sep;1(3):141–145. [PubMed] [Google Scholar]
  7. Murray J. F. The white plague: down and out, or up and coming? J. Burns Amberson lecture. Am Rev Respir Dis. 1989 Dec;140(6):1788–1795. doi: 10.1164/ajrccm/140.6.1788. [DOI] [PubMed] [Google Scholar]
  8. Nauclér A., Andreasson P. A., Costa C. M., Thorstensson R., Biberfeld G. HIV-2-associated AIDS and HIV-2 seroprevalence in Bissau, Guinea-Bissau. J Acquir Immune Defic Syndr. 1989;2(1):88–93. [PubMed] [Google Scholar]
  9. Odehouri K., De Cock K. M., Krebs J. W., Moreau J., Rayfield M., McCormick J. B., Schochetman G., Bretton R., Bretton G., Ouattara D. HIV-1 and HIV-2 infection associated with AIDS in Abidjan, Côte d'Ivoire. AIDS. 1989 Aug;3(8):509–512. doi: 10.1097/00002030-198908000-00004. [DOI] [PubMed] [Google Scholar]
  10. Osterholm M. T., Pierson L. M., White K. E., Libby T. A., Kuritsky J. N., McCullough J. G. The risk of subsequent transmission of Hemophilus influenzae type B disease among children in day care. Results of a two-year statewide prospective surveillance and contact survey. N Engl J Med. 1987 Jan 1;316(1):1–5. doi: 10.1056/NEJM198701013160101. [DOI] [PubMed] [Google Scholar]
  11. Poulsen A. G., Kvinesdal B., Aaby P., Mølbak K., Frederiksen K., Dias F., Lauritzen E. Prevalence of and mortality from human immunodeficiency virus type 2 in Bissau, West Africa. Lancet. 1989 Apr 15;1(8642):827–831. doi: 10.1016/s0140-6736(89)92281-2. [DOI] [PubMed] [Google Scholar]
  12. Rieder H. L., Cauthen G. M., Kelly G. D., Bloch A. B., Snider D. E., Jr Tuberculosis in the United States. JAMA. 1989 Jul 21;262(3):385–389. [PubMed] [Google Scholar]
  13. Romieu I., Marlink R., Kanki P., M'Boup S., Essex M. HIV-2 link to AIDS in West Africa. J Acquir Immune Defic Syndr. 1990;3(3):220–230. [PubMed] [Google Scholar]
  14. Selwyn P. A., Hartel D., Lewis V. A., Schoenbaum E. E., Vermund S. H., Klein R. S., Walker A. T., Friedland G. H. A prospective study of the risk of tuberculosis among intravenous drug users with human immunodeficiency virus infection. N Engl J Med. 1989 Mar 2;320(9):545–550. doi: 10.1056/NEJM198903023200901. [DOI] [PubMed] [Google Scholar]

Articles from BMJ : British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES