Skip to main content
British Medical Journal logoLink to British Medical Journal
. 1975 Jan 25;1(5951):189–191. doi: 10.1136/bmj.1.5951.189

The HL-A system in asbestos workers.

J A Merchant, P T Klouda, C A Soutar, W R Parkes, S D Lawler, M Turner-Warwick
PMCID: PMC1672170  PMID: 1111741

Abstract

In a study of the HL-A system in 56 selected asbestos workers referred to the Pneumoconiosis Medical Panel with definite or suspected asbestosis, the W 27 antigen was found more often than among a control population. Six of the 10 asbestos workers with the W 27 antigen had definite radiographic evidence of asbestosis compared to 13 out of 46 without the W 27 antigen. These observations, if confirmed, suggest that the W 27 antigen may provide a useful marker of an enhanced susceptibility to the tissue-damaging effects of asbestos dust.

Full text

PDF
189

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brewerton D. A., Caffrey M., Nicholls A., Walters D., James D. C. Acute anterior uveitis and HL-A 27. Lancet. 1973 Nov 3;302(7836):994–996. doi: 10.1016/s0140-6736(73)91090-8. [DOI] [PubMed] [Google Scholar]
  2. Brewerton D. A., Hart F. D., Nicholls A., Caffrey M., James D. C., Sturrock R. D. Ankylosing spondylitis and HL-A 27. Lancet. 1973 Apr 28;1(7809):904–907. doi: 10.1016/s0140-6736(73)91360-3. [DOI] [PubMed] [Google Scholar]
  3. Caffrey M. F., James D. C. Human lymphocyte antigen association in ankylosing spondylitis. Nature. 1973 Mar 9;242(5393):121–121. doi: 10.1038/242121a0. [DOI] [PubMed] [Google Scholar]
  4. Gelsthorpe K., Doughty R. W. A new HL-A antigen: TY. Tissue Antigens. 1973;3(4):316–322. doi: 10.1111/j.1399-0039.1973.tb01009.x. [DOI] [PubMed] [Google Scholar]
  5. Lippmann M., Eckert H. L., Hahon N., Morgan W. K. Circulating antinuclear and rheumatoid factors in coal miners. A prevalence study in Pennsylvania and West Virginia. Ann Intern Med. 1973 Dec;79(6):807–811. doi: 10.7326/0003-4819-79-6-807. [DOI] [PubMed] [Google Scholar]
  6. Pernis B., Vigliani E. C., Selikoff I. J. Rheumatoid factor in serum of individuals exposed to asbestos. Ann N Y Acad Sci. 1965 Dec 31;132(1):112–120. doi: 10.1111/j.1749-6632.1965.tb41094.x. [DOI] [PubMed] [Google Scholar]
  7. Rossiter C. E. Evidence of dose-response relation in pneumoconiosis. 1. Trans Soc Occup Med. 1972 Jul;22(3):83–87. doi: 10.1093/occmed/22.1.83. [DOI] [PubMed] [Google Scholar]
  8. Schlosstein L., Terasaki P. I., Bluestone R., Pearson C. M. High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med. 1973 Apr 5;288(14):704–706. doi: 10.1056/NEJM197304052881403. [DOI] [PubMed] [Google Scholar]
  9. Soutar C. A., Turner-Warwick M., Parkes W. R. Circulating antinuclear antibody and rheumatoid factor in coal pneumoconiosis. Br Med J. 1974 Jul 20;3(5924):145–147. doi: 10.1136/bmj.3.5924.145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Turner-Warwick M., Parkes W. R. Circulating rheumatoid and antinuclear factors in asbestos workers. Br Med J. 1970 Aug 29;3(5721):492–495. doi: 10.1136/bmj.3.5721.492. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES