Abstract
The nature of the original renal disease was determined in 403 consecutive cases of end-stage renal failure, in 317 of which the clinical diagnosis was corroborated by histological examination of the kidney. Five diseases accounted for 20 or more cases--glomerulonephritis (31% of the total), analgesic nephropathy (29%), primary vesicoureteral reflux (8%), essential hypertension (6%), and polycystic kidneys (5%). In only four cases did renal failure result from chronic pyelonephritis without a demonstrable primary cause. Greater use of micturating cystography and cystoscopy and routine urine testing for salicylate are advocated for earlier diagnosis of the major causes of "pyelonephritis". The incidence of end-stage renal failure in people aged 15-55 in New South Wales was estimated to be at least 34 new cases per million of total population each year.
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Selected References
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- Bell D., Kerr D. N., Swinney J., Yeates W. K. Analgesic nephropathy. Clinical course after withdrawal of phenacetin. Br Med J. 1969 Aug 16;3(5667):378–382. doi: 10.1136/bmj.3.5667.378. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Blackman J. E., Gibson G. R., Lavan J. N., Learoyd H. M., Posen S. Urinary calculi and the consumption of analgesics. Br Med J. 1967 Jun 24;2(5555):800–802. doi: 10.1136/bmj.2.5555.800. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Branch R. A., Clark G. W., Cochrane A. L., Jones J. H., Scarborough H. Incidence of uraemia and requirements for maintenance haemodialysis. Br Med J. 1971 Jan 30;1(5743):249–254. doi: 10.1136/bmj.1.5743.249. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burry A. F. A profile of renal disease in Queensland: results of an autopsy survey. Med J Aust. 1966 May 14;1(20):826–834. doi: 10.5694/j.1326-5377.1966.tb72874.x. [DOI] [PubMed] [Google Scholar]
- Clunie G. J., Hartley L. C., Ribush N. T., Emmerson B. T., Morgan T. O. An integrated service for the treatment of irreversible renal failure. Med J Aust. 1971 Aug 21;2(8):403–408. doi: 10.5694/j.1326-5377.1971.tb50632.x. [DOI] [PubMed] [Google Scholar]
- Dawborn J. K., Fairley K. F., Kincaid-Smith P., King W. E. The association of peptic ulceration, chronic renal disease, and analgesic abuse. Q J Med. 1966 Jan;35(137):69–83. [PubMed] [Google Scholar]
- Doak P. B., Bowie E. A., Dalton N. T., Douglas R., Duke A. J., Maclaurin C. H., Montgomerie J. Z., North J. D., Smith H. L., Sorrell V. F. Four years' experience with cadaveric renal transplantation. N Z Med J. 1971 Mar;73(466):117–123. [PubMed] [Google Scholar]
- Emmerson B. T. Chronic lead nephropathy. Kidney Int. 1973 Jul;4(1):1–5. doi: 10.1038/ki.1973.73. [DOI] [PubMed] [Google Scholar]
- Gault M. H., Dossetor J. B. Chronic pyelonephritis: relative incidence in transplant recipients. N Engl J Med. 1966 Oct 13;275(15):813–816. doi: 10.1056/NEJM196610132751504. [DOI] [PubMed] [Google Scholar]
- Gault M. H., Rudwal T. C., Engles W. D., Dossetor J. B. Syndrome associated with the abuse of analgesics. Ann Intern Med. 1968 Apr;68(4):906–925. doi: 10.7326/0003-4819-68-4-906. [DOI] [PubMed] [Google Scholar]
- Gillies M. A., Skyring A. Gastric and duodenal ulcer. The association between aspirin ingestion, smoking and family history of ulcer. Med J Aust. 1969 Aug 9;2(6):280–285. doi: 10.5694/j.1326-5377.1969.tb105725.x. [DOI] [PubMed] [Google Scholar]
- HODSON C. J. The radiological diagnosis of pyelonephritis. Proc R Soc Med. 1959 Aug;52:669–672. doi: 10.1177/003591575905200819. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KIMMELSTIEL P., KIM O. J., BERES J. A., WELLMAN K. Chronic pyelonephritis. Am J Med. 1961 Apr;30:589–607. doi: 10.1016/0002-9343(61)90082-1. [DOI] [PubMed] [Google Scholar]
- KINCAID-SMITH P., McMICHAEL J., MURPHY E. A. The clinical course and pathology of hypertension with papilloedema (malignant hypertension). Q J Med. 1958 Jan;27(105):117–153. [PubMed] [Google Scholar]
- Kincaid-Smith P. Pathogenesis of the renal lesion associated with the abuse of analgesics. Lancet. 1967 Apr 22;1(7495):859–862. doi: 10.1016/s0140-6736(67)91425-0. [DOI] [PubMed] [Google Scholar]
- Lowrie E. G., Lazarus J. M., Mocelin A. J., Bailey G. L., Hampers C. L., Wilson R. E., Merrill J. P. Survival of patients undergoing chronic hemodialysis and renal transplantation. N Engl J Med. 1973 Apr 26;288(17):863–867. doi: 10.1056/NEJM197304262881701. [DOI] [PubMed] [Google Scholar]
- Lyon R. P., Marshall S., Tanagho E. A. The ureteral orifice: its configuration and competency. J Urol. 1969 Oct;102(4):504–509. doi: 10.1016/s0022-5347(17)62184-0. [DOI] [PubMed] [Google Scholar]
- MILOJCIC B. Epidemic of chronic nephritis of unknown aetiology. Br Med J. 1960 Jan 23;1(5168):244–245. doi: 10.1136/bmj.1.5168.244. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McGeown M. G. Chronic renal failure in Northern Ireland, 1968-70. A prospective survey. Lancet. 1972 Feb 5;1(7745):307–310. doi: 10.1016/s0140-6736(72)90305-4. [DOI] [PubMed] [Google Scholar]
- Murray R. M., Lawson D. H., Linton A. L. Analgesic nephropathy: clinical syndrome and prognosis. Br Med J. 1971 Feb 27;1(5747):479–482. doi: 10.1136/bmj.1.5747.479. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nordenfelt O. Deaths from renal failure in abusers of phenacetin-containing drugs. Acta Med Scand. 1972 Jan-Feb;191(1-2):11–16. [PubMed] [Google Scholar]
- Pendreigh D. M., Howitt L. F., Macdougall A. J., Robson J. S., Heasman M. A., Kennedy A. C., MacLeod M., Stewart W. K. Survey of chronic renal failure in Scotland. Lancet. 1972 Feb 5;1(7745):304–307. doi: 10.1016/s0140-6736(72)90304-2. [DOI] [PubMed] [Google Scholar]
- Pindborg T., Rojel J., Sorensen H. R., Kemp E. Requirements for the treatment of terminal uremia in a Danish population of one million. Scand J Urol Nephrol. 1973;7(2):196–199. doi: 10.3109/00365597309133702. [DOI] [PubMed] [Google Scholar]
- Rao M. M., Lawrence J. R., Barratt L. J., Miller C. D., Knight P. R., Higgins B. A., Proudman W. D., Slavotinek A. H., Harris J. D., Elmslie R. G. Renal transplantation in South Australia. Med J Aust. 1972 Jan 29;1(5):209–214. [PubMed] [Google Scholar]
- Schechter H., Leonard C. D., Scribner B. H. Chronic pyelonephritis as a cause of renal failure in dialysis candidates. Analysis of 173 patients. JAMA. 1971 Apr 19;216(3):514–517. [PubMed] [Google Scholar]
- Sheil A. G., Stewart J. H., Johnson J. R., May J., Storey B. G., Rogers J. H., Charlesworth J. A., Hurley B. P., Tiller D., Mahony J. F. Cadaveric donor renal transplantation. Med J Aust. 1972 Jan 29;1(5):205–209. doi: 10.5694/j.1326-5377.1972.tb46764.x. [DOI] [PubMed] [Google Scholar]
- Steele T. W., Edwards K. D. Analgesic nephropathy. Changes in various parameters of renal function following cessation of analgesic abuse. Med J Aust. 1971 Jan 23;1(4):181–187. [PubMed] [Google Scholar]
- TALBOTT J. H., TERPLAN K. L. The kidney in gout. Medicine (Baltimore) 1960 Dec;39:405–467. [PubMed] [Google Scholar]
