Abstract
Thirty-five asthmatic patients (average age 28 years) who attended a pulmonary function laboratory when their mean ratio of forced expiratory volume in one second: forced vital capacity was 81 per cent (within the normal range for their age group) had arterial hypoxaemia and hypocapnia. These were probably secondary to lung hyperinflation and pulmonary ventilation/perfusion imbalance. The pulmonary abnormalities of bronchial asthma are not always detected by simple spirometric tests and the results of such tests should be interpreted cautiously.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cade J. F., Pain M. C. Pulmonary function during clinical remission of asthma. How reversible is asthma? Aust N Z J Med. 1973 Dec;3(6):545–551. doi: 10.1111/j.1445-5994.1973.tb04293.x. [DOI] [PubMed] [Google Scholar]
- Diament M. L., Palmer K. N. An analysis of pre-operative PaO2 in a general surgical population. Thorax. 1969 Jan;24(1):126–128. doi: 10.1136/thx.24.1.126. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Higgins M. W., Keller J. B. Seven measures of ventilatory lung function. Population values and a comparison of their ability to discriminate between persons with and without chronic respiratory symptoms and disease, Tecumseh, Michigan. Am Rev Respir Dis. 1973 Aug;108(2):258–272. doi: 10.1164/arrd.1973.108.2.258. [DOI] [PubMed] [Google Scholar]
- Levine G., Housley E., MacLeod P., Macklem P. T. Gas exchange abnormalities in mild bronchitis and asymptomatic asthma. N Engl J Med. 1970 Jun 4;282(23):1277–1282. doi: 10.1056/NEJM197006042822301. [DOI] [PubMed] [Google Scholar]
- Mayfield J. D., Paez P. N., Nicholson D. P. Static and dynamic lung volumes and ventilation-perfusion abnormality in adult asthma. Thorax. 1971 Sep;26(5):591–596. doi: 10.1136/thx.26.5.591. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Safirstein B. H. Aspergilloma consequent to allergic bronchopulmonary aspergillosis. Am Rev Respir Dis. 1973 Oct;108(4):940–943. doi: 10.1164/arrd.1973.108.4.940. [DOI] [PubMed] [Google Scholar]