Abstract
In 78 patients with chronic asthma the increase in forced expiratory volume in one second (FEV-1) after the administration by intermittent positive-pressure ventilation (I.P.P.V.) of 10 mg of salbutamol was compared with that recorded after the inhalation of a conventional dose (200 mug) from a pressurized canister. The mean increase was significantly greater after I.P.P.V. administration, and the superiority of this method was greatest in patients with the lowest pretreatment FEV-1.
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Selected References
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- COHEN A. A., HALE F. C. COMPARATIVE EFFECTS OF ISOPROTERENOL AEROSOLS ON AIRWAY RESISTANCE IN OBSTRUCTIVE PULMONARY DISEASES. Am J Med Sci. 1965 Mar;249:309–315. doi: 10.1097/00000441-196503000-00010. [DOI] [PubMed] [Google Scholar]
- Choo-Kang Y. F., Tribe A. E., Grant I. W. Salbutamol by intermittent positive pressure ventilation in status asthmaticus. Scott Med J. 1974 Jul;19(4):191–195. doi: 10.1177/003693307401900407. [DOI] [PubMed] [Google Scholar]
- HUME K. M., GANDEVIA B. Forced expiratory volume before and after isoprenaline. Thorax. 1957 Sep;12(3):276–278. doi: 10.1136/thx.12.3.276. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Inman W. H., Adelstein A. M. Rise and fall of asthma mortality in England and Wales in relation to use of pressurised aerosols. Lancet. 1969 Aug 9;2(7615):279–285. doi: 10.1016/s0140-6736(69)90051-8. [DOI] [PubMed] [Google Scholar]
- Shenfield G. M., Evans M. E., Walker S. R., Paterson J. W. The fate of nebulized salbutamol (albuterol) administered by intermittent positive pressure respiration to asthmatic patients. Am Rev Respir Dis. 1973 Sep;108(3):501–505. doi: 10.1164/arrd.1973.108.3.501. [DOI] [PubMed] [Google Scholar]
- Stolley P. D. Asthma mortality. Why the United States was spared an epidemic of deaths due to asthma. Am Rev Respir Dis. 1972 Jun;105(6):883–890. doi: 10.1164/arrd.1972.105.6.883. [DOI] [PubMed] [Google Scholar]
