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British Medical Journal logoLink to British Medical Journal
. 1975 May 31;2(5969):471–473. doi: 10.1136/bmj.2.5969.471

Anabolic steroids in athelics: crossover double-blind trial on weightlifters.

D L Freed, A J Banks, D Longson, D M Burley
PMCID: PMC1673411  PMID: 125133

Abstract

Thirteen experienced male weightlifters taking high-protein diets and regular exercise took part in a double-blind crossover trial of methandienone 10 or 25 mg/day to seeif the drug improved athletic performance. Their improvemments were significantly greater on methandienone than on placebo; their body weights rose (though this seemed to be associated with water retention); and systolic blood pressure rose significantly. Methandienone caused many side effects, and three men had to withdraw because of them. All side effects disappeared after the drug was stopped. Anabolic steroids are effective only when given combination with exercise and high-protein diet.We deprecate their use in athletics but can suggest no way of stopping it.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DESAULLES P. A., KRAEHENBUEHL C., SCHULER W., BEIN H. J. [Experimental study of dianabol, a new anabolic agent. 17 alpha-Methyl-17 beta-hydroxy-androstane-1,4-diene-3-one]. Schweiz Med Wochenschr. 1959 Dec 12;89:1313–1318. [PubMed] [Google Scholar]
  2. Fowler W. M., Jr, Gardner G. W., Egstrom G. H. Effect of an anabolic steroid on physical performance of young men. J Appl Physiol. 1965 Sep;20(5):1038–1040. doi: 10.1152/jappl.1965.20.5.1038. [DOI] [PubMed] [Google Scholar]
  3. JAMES V. H., LANDON J., WYNN V. Effect of an anabolic steroid (methandienone) on the metabolism of cortisol in the human. J Endocrinol. 1962 Oct;25:211–220. doi: 10.1677/joe.0.0250211. [DOI] [PubMed] [Google Scholar]
  4. Johnson L. C., Fisher G., Silvester L. J., Hofheins C. C. Anabolic steroid: effects on strength, body weight, oxygen uptake and spermatogenesis upon mature males. Med Sci Sports. 1972 Spring;4(1):43–45. [PubMed] [Google Scholar]
  5. Johnson L. C., O'Shea J. P. Anabolic steroid: effects on strength development. Science. 1969 May 23;164(3882):957–959. doi: 10.1126/science.164.3882.957. [DOI] [PubMed] [Google Scholar]
  6. LIDDLE G. W., BURKE H. A., Jr Anabolic steroids in clinical medicine. Helv Med Acta. 1960 Dec;27:504–513. [PubMed] [Google Scholar]
  7. WYNN V., LANDON J., KAWERAU E. Studies of hepatic function during methandienone therapy. Lancet. 1961 Jan 14;1(7168):69–75. doi: 10.1016/s0140-6736(61)92118-3. [DOI] [PubMed] [Google Scholar]
  8. Wade N. Anabolic Steroids: Doctors Denounce Them, but Athletes Aren't Listening. Science. 1972 Jun 30;176(4042):1399–1403. doi: 10.1126/science.176.4042.1399. [DOI] [PubMed] [Google Scholar]

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