Skip to main content
Applied and Environmental Microbiology logoLink to Applied and Environmental Microbiology
. 1995 Mar;61(3):1133–1137. doi: 10.1128/aem.61.3.1133-1137.1995

Evidence that water transmits Vibrio vulnificus biotype 2 infections to eels.

C Amaro 1, E G Biosca 1, B Fouz 1, E Alcaide 1, C Esteve 1
PMCID: PMC167367  PMID: 7793914

Abstract

Vibrio vulnificus biotype 2 is classically considered an obligate eel pathogen. However, it has recently been associated with one human septicemic case. In this paper, the opportunistic behavior of this pathogen is discussed. The bacterium can survive alone in brackish water or attached to eel surfaces for at least 14 days. It is able to spread through water and infect healthy eels by using skin as a portal of entry. These results suggest that water and infected eels may act as reservoirs of infection. A capsule seems to be essential for waterborne infectivity, which would explain why cells recovered from naturally diseased eels give rise to pure cultures of opaque colonies. The spread of the disease is dependent on temperature and water salinity, thus suggesting a method to reduce the risk of epizootics and that of infection for humans.

Full Text

The Full Text of this article is available as a PDF (205.4 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amaro C., Biosca E. G., Fouz B., Garay E. Electrophoretic analysis of heterogeneous lipopolysaccharides from various strains of Vibrio vulnificus biotypes 1 and 2 by silver staining and immunoblotting. Curr Microbiol. 1992 Aug;25(2):99–104. doi: 10.1007/BF01570967. [DOI] [PubMed] [Google Scholar]
  2. Amaro C., Biosca E. G., Fouz B., Toranzo A. E., Garay E. Role of iron, capsule, and toxins in the pathogenicity of Vibrio vulnificus biotype 2 for mice. Infect Immun. 1994 Feb;62(2):759–763. doi: 10.1128/iai.62.2.759-763.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Biosca E. G., Llorens H., Garay E., Amaro C. Presence of a capsule in Vibrio vulnificus biotype 2 and its relationship to virulence for eels. Infect Immun. 1993 May;61(5):1611–1618. doi: 10.1128/iai.61.5.1611-1618.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bradshaw C. M., Richard A. S., Sigel M. M. IgM antibodies in fish mucus. Proc Soc Exp Biol Med. 1971 Apr;136(4):1122–1124. doi: 10.3181/00379727-136-35443. [DOI] [PubMed] [Google Scholar]
  5. Kelly M. T. Effect of temperature and salinity on Vibrio (Beneckea) vulnificus occurrence in a Gulf Coast environment. Appl Environ Microbiol. 1982 Oct;44(4):820–824. doi: 10.1128/aem.44.4.820-824.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Oliver J. D., Warner R. A., Cleland D. R. Distribution and ecology of Vibrio vulnificus and other lactose-fermenting marine vibrios in coastal waters of the southeastern United States. Appl Environ Microbiol. 1982 Dec;44(6):1404–1414. doi: 10.1128/aem.44.6.1404-1414.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Oliver J. D., Warner R. A., Cleland D. R. Distribution of Vibrio vulnificus and other lactose-fermenting vibrios in the marine environment. Appl Environ Microbiol. 1983 Mar;45(3):985–998. doi: 10.1128/aem.45.3.985-998.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Tison D. L., Nishibuchi M., Greenwood J. D., Seidler R. J. Vibrio vulnificus biogroup 2: new biogroup pathogenic for eels. Appl Environ Microbiol. 1982 Sep;44(3):640–646. doi: 10.1128/aem.44.3.640-646.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Veenstra J., Rietra P. J., Stoutenbeek C. P., Coster J. M., de Gier H. H., Dirks-Go S. Infection by an indole-negative variant of Vibrio vulnificus transmitted by eels. J Infect Dis. 1992 Jul;166(1):209–210. doi: 10.1093/infdis/166.1.209. [DOI] [PubMed] [Google Scholar]

Articles from Applied and Environmental Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES