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. 1995 May;61(5):2020–2022. doi: 10.1128/aem.61.5.2020-2022.1995

Emergence of nylon oligomer degradation enzymes in Pseudomonas aeruginosa PAO through experimental evolution.

I D Prijambada 1, S Negoro 1, T Yomo 1, I Urabe 1
PMCID: PMC167468  PMID: 7646041

Abstract

Through selective cultivation with 6-aminohexanoate linear dimer, a by-product of nylon-6 manufacture, as the sole source of carbon and nitrogen, Pseudomonas aeruginosa PAO, which initially has no enzyme activity to degrade this xenobiotic compound, was successfully expanded in its metabolic ability. Two new enzyme activities, 6-aminohexanoate cyclic dimer hydrolase and 6-aminohexanoate dimer hydrolase, were detected in the adapted strains.

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Selected References

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