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. 1975 Dec 20;4(5998):694–697. doi: 10.1136/bmj.4.5998.694

Bromocriptine treatment of female infertility: report of 13 pregnancies.

M O Thorner, G M Besser, A Jones, J Dacie, A E Jones
PMCID: PMC1675785  PMID: 1203727

Abstract

Thirteen pregnancies occurred in 12 women who were treated with bromocriptine for infertility. Pretreatment prolactin levels were recorded in 11 patients and were normal in three. Five patients had suspected pituitary tumours, and they received irradiation to prevent swelling of the pituitary and the consequent visual field defects caused by the pressure of the swollen gland on the optic nerve. Ten of the 13 pregnancies have come to term, and all the babies were normal. When a patient with a pituitary tumour developed a visual field defect in the 38th week of pregnancy labour was induced and the defect disappeared after delivery. No multiple pregnancies occurred and there were no major complications.

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Selected References

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  1. Burke C. W., Joplin G. F., Fraser R. Pituitary tumour treated by pituitary implantation of yttrium 90 during or before pregnancy (two cases). Proc R Soc Med. 1972 May;65(5):486–488. [PMC free article] [PubMed] [Google Scholar]
  2. Gemzell C. Induction of ovulation in infertile women with pituitary tumors. Am J Obstet Gynecol. 1975 Feb 1;121(3):311–315. doi: 10.1016/0002-9378(75)90004-6. [DOI] [PubMed] [Google Scholar]
  3. Hall R., Ormston B. J., Besser G. M., Cryer R. J. The thyrotrophin-releasing hormone test in diseases of the pituitary and hypothalamus. Lancet. 1972 Apr 8;1(7754):759–763. doi: 10.1016/s0140-6736(72)90518-1. [DOI] [PubMed] [Google Scholar]
  4. Joplin G. F., Jackson R. A., Arnot R. N., Burke C. W., Doyle F. H., Harsoulis P., Lewis P. D., Macerlean D. P., Marshall J. C., Van Noorden S. The effect of yttrium-90 implantation on endocrine function and visual fields in patients with "functionless" pituitary tumors, with biopsy and radiological findings. Clin Endocrinol (Oxf) 1975 Mar;4(2):139–163. doi: 10.1111/j.1365-2265.1975.tb01522.x. [DOI] [PubMed] [Google Scholar]
  5. Lynch D. M., Green E. A., McFadzean J. A., Pugh I. M. Trichuris trichiura infestations in the United Kingdom and treatment with difetarsone. Br Med J. 1972 Oct 14;4(5832):73–76. doi: 10.1136/bmj.4.5832.73. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. MATTINGLY D. A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma. J Clin Pathol. 1962 Jul;15:374–379. doi: 10.1136/jcp.15.4.374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. McNeilly A. S., Hagen C. Prolactin, TSH, LH and FSH responses to a combined LHRH-TRH test at different stages of the menstrual cycle. Clin Endocrinol (Oxf) 1974 Oct;3(4):427–435. doi: 10.1111/j.1365-2265.1974.tb02813.x. [DOI] [PubMed] [Google Scholar]
  8. Monro P., Mair W. G. Radiation effects on the human central nervous system 14 weeks after x-radiation. Acta Neuropathol. 1968 Nov 1;11(4):267–274. doi: 10.1007/BF00686723. [DOI] [PubMed] [Google Scholar]
  9. Mortimer C. H., Besser G. M., McNeilly A. S., Marshall J. C., Harsoulis P., Tunbridge W. M., Gomez-Pan A., Hall R. Luteinizing hormone and follicle stimulating hormone-releasing hormone test in patients with hypothalamic-pituitary-gonadal dysfunction. Br Med J. 1973 Oct 13;4(5884):73–77. doi: 10.1136/bmj.4.5884.73. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Ormston B. J., Cryer R. J., Garry R., Besser G. M., Hall R. Thyrotrophin-releasing hormone as a thyroid-function test. Lancet. 1971 Jul 3;2(7714):10–14. doi: 10.1016/s0140-6736(71)90005-5. [DOI] [PubMed] [Google Scholar]
  11. Swanson H. A., Du Boulay G. Borderline variants of the normal pituitary fossa. Br J Radiol. 1975 May;48(569):366–369. doi: 10.1259/0007-1285-48-569-366. [DOI] [PubMed] [Google Scholar]
  12. Thorner M. O., McNeilly A. S., Hagan C., Besser G. M. Long-term treatment of galactorrhoea and hypogonadism with bromocriptine. Br Med J. 1974 May 25;2(5916):419–422. doi: 10.1136/bmj.2.5916.419. [DOI] [PMC free article] [PubMed] [Google Scholar]

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