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. 1975 Dec 20;4(5998):678–680. doi: 10.1136/bmj.4.5998.678

The immunological hazard of Cushing's syndrome.

S Britton, M Thorén, H E Sjoberg
PMCID: PMC1675825  PMID: 1081900

Abstract

A 24-year-old woman was found to have cryptococcal meningitis and Cushing's syndrome due to an adrenal adenoma. Her meningitis was successfully arrested with fluorouracil. Treatment with metyrapone decreased her cortisol production and produced clinical remission of Cushing's syndrome. On admission her peripheral T lymphocytes were few and hyporeactive. When the overproduction of cortisol ceased the numbers of T lymphocytes and their reactivity returned to normal and she developed in-vitro lymphocyte responsiveness to the cryptococci.

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Selected References

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