Abstract
Tryptic activity disappeared and trypsin was no longer detected with an antitrypsin antiserum in the large intestines of gnotobiotic rats and mice monoassociated with a human-derived strain of Bacteroides distasonis, whereas tryptic activity was not modified in the small intestines. This function was shown to be strain specific.
Full Text
The Full Text of this article is available as a PDF (192.3 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bohe M., Borgström A., Genell S., Ohlsson K. Determination of immunoreactive trypsin, pancreatic elastase and chymotrypsin in extracts of human feces and ileostomy drainage. Digestion. 1983;27(1):8–15. doi: 10.1159/000198913. [DOI] [PubMed] [Google Scholar]
- Corthier G., Muller M. C., Elmer G. W., Lucas F., Dubos-Ramaré F. Interrelationships between digestive proteolytic activities and production and quantitation of toxins in pseudomembranous colitis induced by Clostridium difficile in gnotobiotic mice. Infect Immun. 1989 Dec;57(12):3922–3927. doi: 10.1128/iai.57.12.3922-3927.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Corthier G., Muller M. C., L'Haridon R. Selective enumeration of Bacteroides vulgatus and B. distasonis organisms in the predominant human fecal flora by using monoclonal antibodies. Appl Environ Microbiol. 1996 Feb;62(2):735–738. doi: 10.1128/aem.62.2.735-738.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Genell S., Gustafsson B. E., Ohlsson K. Quantitation of active pancreatic endopeptidases in the intestinal contents of germfree and conventional rats. Scand J Gastroenterol. 1976;11(8):757–762. [PubMed] [Google Scholar]
- Macfarlane G. T., Allison C., Gibson S. A., Cummings J. H. Contribution of the microflora to proteolysis in the human large intestine. J Appl Bacteriol. 1988 Jan;64(1):37–46. doi: 10.1111/j.1365-2672.1988.tb02427.x. [DOI] [PubMed] [Google Scholar]
- Midtvedt T., Carlstedt-Duke B., Höverstad T., Midtvedt A. C., Norin K. E., Saxerholt H. Establishment of a biochemically active intestinal ecosystem in ex-germfree rats. Appl Environ Microbiol. 1987 Dec;53(12):2866–2871. doi: 10.1128/aem.53.12.2866-2871.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Norin K. E., Gustafsson B. E., Lindblad B. S., Midtvedt T. The establishment of some microflora associated biochemical characteristics in feces from children during the first years of life. Acta Paediatr Scand. 1985 Mar;74(2):207–212. doi: 10.1111/j.1651-2227.1985.tb10951.x. [DOI] [PubMed] [Google Scholar]
- Norin K. E., Gustafsson B. E., Midtvedt T. Strain differences in faecal tryptic activity of germ-free and conventional rats. Lab Anim. 1986 Jan;20(1):67–69. doi: 10.1258/002367786781062188. [DOI] [PubMed] [Google Scholar]
- Norin K. E., Midtvedt T., Gustafsson B. E. Influence of intestinal microflora on the tryptic activity during lactation in rats. Lab Anim. 1986 Jul;20(3):234–237. doi: 10.1258/002367786780865656. [DOI] [PubMed] [Google Scholar]
- Norin K. E., Persson A. K., Saxerholt H., Midtvedt T. Establishment of Lactobacillus and Bifidobacterium species in germfree mice and their influence on some microflora-associated characteristics. Appl Environ Microbiol. 1991 Jun;57(6):1850–1852. doi: 10.1128/aem.57.6.1850-1852.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
- van de Merwe J. P., Mol G. J. Levels of trypsin and alpha-chymotrypsin in feces from patients with Crohn's disease. Digestion. 1982;24(1):1–4. doi: 10.1159/000198767. [DOI] [PubMed] [Google Scholar]