Abstract
OBJECTIVES--To study the prevalence of asthma (asthma symptoms and bronchial hyperresponsiveness) in Swedish cross country skiers compared with non-skiers and monitor changes in symptoms and bronchial hyperresponsiveness during the year. DESIGN--Cross sectional study during the winter ski season and in the summer. SETTING--Six ski clubs for élite skiers (total 47) in two different areas of Sweden. SUBJECTS--42 élite cross country skiers and 29 non-skiing referents. MAIN OUTCOME MEASURES--Bronchial responsiveness, asthma symptoms, and lung function. RESULTS--Bronchial responsiveness was significantly greater and asthma symptoms more prevalent in the skiers than in the referents. There was no difference in bronchial responsiveness within either group between winter and summer. 15 of the 42 skiers used antiasthmatic drugs regularly and 23 had a combination of asthma symptoms and hyperresponsive airways or physician diagnosed asthma, or both. Altogether 33 skiers had symptoms of asthma or bronchial hyperresponsiveness. One of the referents had symptoms of asthma and bronchial hyperresponsiveness, and none used antiasthmatic drugs regularly. CONCLUSIONS--Asthma, asthma-like symptoms, and bronchial hyperresponsiveness are much more common in cross country skiers than in the general population and non-skiers. Strenuous exercise at low temperatures entailing breathing large volumes of cold air is the most probable explanation of persistent asthma in skiers.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Amirav I., Plit M. Temperature and humidity modify airway response to inhaled histamine in normal subjects. Am Rev Respir Dis. 1989 Nov;140(5):1416–1420. doi: 10.1164/ajrccm/140.5.1416. [DOI] [PubMed] [Google Scholar]
- Beermann D. H., Butler W. R., Hogue D. E., Fishell V. K., Dalrymple R. H., Ricks C. A., Scanes C. G. Cimaterol-induced muscle hypertrophy and altered endocrine status in lambs. J Anim Sci. 1987 Dec;65(6):1514–1524. doi: 10.2527/jas1987.6561514x. [DOI] [PubMed] [Google Scholar]
- Freeman W., Packe G. E., Cayton R. M. Effect of nebulised salbutamol on maximal exercise performance in men with mild asthma. Thorax. 1989 Nov;44(11):942–947. doi: 10.1136/thx.44.11.942. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hedenström H., Malmberg P., Agarwal K. Reference values for lung function tests in females. Regression equations with smoking variables. Bull Eur Physiopathol Respir. 1985 Nov-Dec;21(6):551–557. [PubMed] [Google Scholar]
- Hedenström H., Malmberg P., Fridriksson H. V. Reference values for lung function tests in men: regression equations with smoking variables. Ups J Med Sci. 1986;91(3):299–310. doi: 10.3109/03009738609178670. [DOI] [PubMed] [Google Scholar]
- Kerrebijn K. F., van Essen-Zandvliet E. E., Neijens H. J. Effect of long-term treatment with inhaled corticosteroids and beta-agonists on the bronchial responsiveness in children with asthma. J Allergy Clin Immunol. 1987 Apr;79(4):653–659. doi: 10.1016/s0091-6749(87)80163-x. [DOI] [PubMed] [Google Scholar]
- Kraan J., Koëter G. H., vd Mark T. W., Sluiter H. J., de Vries K. Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline. J Allergy Clin Immunol. 1985 Oct;76(4):628–636. doi: 10.1016/0091-6749(85)90786-9. [DOI] [PubMed] [Google Scholar]
- Larsson K., Hedenström H., Malmberg P. Learning effects, variation during office hours and reproducibility of static and dynamic spirometry. Respiration. 1987;51(3):214–222. doi: 10.1159/000195204. [DOI] [PubMed] [Google Scholar]
- Larsson K., Martinsson A., Hjemdahl P. Influence of beta-adrenergic receptor function during terbutaline treatment on allergen sensitivity and bronchodilator response to terbutaline in asthmatic subjects. Chest. 1992 Apr;101(4):953–960. doi: 10.1378/chest.101.4.953. [DOI] [PubMed] [Google Scholar]
- Larsson L., Boëthius G., Uddenfeldt M. Differences in utilization of asthma drugs between two neighbouring Swedish provinces: relation to symptom reporting. Eur Respir J. 1993 Feb;6(2):198–203. [PubMed] [Google Scholar]
- Lundbäck B., Nyström L., Rosenhall L., Stjernberg N. Obstructive lung disease in northern Sweden: respiratory symptoms assessed in a postal survey. Eur Respir J. 1991 Mar;4(3):257–266. [PubMed] [Google Scholar]
- Malmberg P., Larsson K., Thunberg S. Increased lung deposition and biological effect of methacholine by use of a drying device for bronchial provocation tests. Eur Respir J. 1991 Jul;4(7):890–898. [PubMed] [Google Scholar]
- Martineau L., Horan M. A., Rothwell N. J., Little R. A. Salbutamol, a beta 2-adrenoceptor agonist, increases skeletal muscle strength in young men. Clin Sci (Lond) 1992 Nov;83(5):615–621. doi: 10.1042/cs0830615. [DOI] [PubMed] [Google Scholar]
- Martinez J. A., Portillo M. P., Larralde J. Anabolic actions of a mixed beta-adrenergic agonist on nitrogen retention and protein turnover. Horm Metab Res. 1991 Dec;23(12):590–593. doi: 10.1055/s-2007-1003762. [DOI] [PubMed] [Google Scholar]
- McKenzie D. C., Rhodes E. C., Stirling D. R., Wiley J. P., Dunwoody D. W., Filsinger I. B., Jang F., Stevens A. Salbutamol and treadmill performance in non-atopic athletes. Med Sci Sports Exerc. 1983;15(6):520–522. [PubMed] [Google Scholar]
- Signorile J. F., Kaplan T. A., Applegate B., Perry A. C. Effects of acute inhalation of the bronchodilator, albuterol, on power output. Med Sci Sports Exerc. 1992 Jun;24(6):638–642. [PubMed] [Google Scholar]
- Strauss R. H., McFadden E. R., Jr, Ingram R. H., Jr, Deal E. C., Jr, Jaeger J. J. Influence of heat and humidity on the airway obstruction induced by exercise in asthma. J Clin Invest. 1978 Feb;61(2):433–440. doi: 10.1172/JCI108954. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Strauss R. H., McFadden E. R., Jr, Ingram R. H., Jr, Jaeger J. J. Enhancement of exercise-induced asthma by cold air. N Engl J Med. 1977 Oct 6;297(14):743–747. doi: 10.1056/NEJM197710062971402. [DOI] [PubMed] [Google Scholar]
- Vathenen A. S., Knox A. J., Higgins B. G., Britton J. R., Tattersfield A. E. Rebound increase in bronchial responsiveness after treatment with inhaled terbutaline. Lancet. 1988 Mar 12;1(8585):554–558. doi: 10.1016/s0140-6736(88)91352-9. [DOI] [PubMed] [Google Scholar]
- Voy R. O. The U.S. Olympic Committee experience with exercise-induced bronchospasm, 1984. Med Sci Sports Exerc. 1986 Jun;18(3):328–330. doi: 10.1249/00005768-198606000-00013. [DOI] [PubMed] [Google Scholar]
- Weiler J. M., Metzger W. J., Donnelly A. L., Crowley E. T., Sharath M. D. Prevalence of bronchial hyperresponsiveness in highly trained athletes. Chest. 1986 Jul;90(1):23–28. doi: 10.1378/chest.90.1.23. [DOI] [PubMed] [Google Scholar]
- van Schayck C. P., Graafsma S. J., Visch M. B., Dompeling E., van Weel C., van Herwaarden C. L. Increased bronchial hyperresponsiveness after inhaling salbutamol during 1 year is not caused by subsensitization to salbutamol. J Allergy Clin Immunol. 1990 Nov;86(5):793–800. doi: 10.1016/s0091-6749(05)80185-x. [DOI] [PubMed] [Google Scholar]