Abstract
A clinically normal horse was anesthetized preparatory to surgery in dorsal recumbency for removal of a retained testicle. After recovery from the anesthetic, the horse was weak in the hind legs, subsequently deteriorated and became unable to rise and died on the eighth day after surgery. On microscopic examination, extensive poliomalacia of the thoracic and lumbar spinal cord was found. It is postulated that this lesion was a result of ischemic insult to the spinal cord during anesthesia and several possible pathogeneses are discussed.
Keywords: Poliomyelomalacia, postanesthetic, equine
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Alexander S. C., Lassen N. A. Cerebral circulatory response to acute brain disease: Implications for anesthetic practice. Anesthesiology. 1970 Jan;32(1):60–68. doi: 10.1097/00000542-197001000-00013. [DOI] [PubMed] [Google Scholar]
- Cordy D. R., East N. E., Lowenstine L. J. Caprine encephalomyelomalacia. Vet Pathol. 1984 May;21(3):269–273. doi: 10.1177/030098588402100301. [DOI] [PubMed] [Google Scholar]
- GELFAN S., TARLOV I. M. Differential vulnerability of spinal cord structures to anoxia. J Neurophysiol. 1955 Mar;18(2):170–188. doi: 10.1152/jn.1955.18.2.170. [DOI] [PubMed] [Google Scholar]
- Gilles F. H., Nag D. Vulnerability of human spinal cord in transient cardiac arrest. Neurology. 1971 Aug;21(8):833–839. doi: 10.1212/wnl.21.8.833. [DOI] [PubMed] [Google Scholar]
- Griffiths I. R., Burns N., Crawford A. R. Early vascular changes in the spinal grey matter following impact injury. Acta Neuropathol. 1978 Jan 19;41(1):33–39. doi: 10.1007/BF00689554. [DOI] [PubMed] [Google Scholar]
- HAYMAKER W., JOHNSTON A. D. Pathology of decompression sickness; a comparison of the lesions in airmen with those in caisson workers and divers. Mil Med. 1955 Sep;117(3):285–306. [PubMed] [Google Scholar]
- Harp J. R., Wollman H. Cerebral metabolic effects of hyperventilation and deliberate hypotension. Br J Anaesth. 1973 Mar;45(3):256–262. doi: 10.1093/bja/45.3.256. [DOI] [PubMed] [Google Scholar]
- Harrison L. H., Colvin B. M., Stuart B. P., Sangster L. T., Gorgacz E. J., Gosser H. S. Paralysis in swine due to focal symmetrical poliomalacia: possible selenium toxicosis. Vet Pathol. 1983 May;20(3):265–273. doi: 10.1177/030098588302000303. [DOI] [PubMed] [Google Scholar]
- McLAURIN R. L., BAILEY O. T., SCHURR P. H., INGRAHAM F. D. Myelomalacia and multiple cavitations of spinal cord secondary to adhesive arachnoiditis; an experimental study. AMA Arch Pathol. 1954 Feb;57(2):138–146. [PubMed] [Google Scholar]
- Osterholm J. L. The pathophysiological response to spinal cord injury. The current status of related research. J Neurosurg. 1974 Jan;40(1):5–33. [PubMed] [Google Scholar]
- Schatzmann U., Meister V., Fankhauser R. Akute Hämatomyelie nach längerer Rückenlage beim Pferd. Schweiz Arch Tierheilkd. 1979 Mar;121(3):149–155. [PubMed] [Google Scholar]