Skip to main content
The Canadian Veterinary Journal logoLink to The Canadian Veterinary Journal
. 1986 May;27(5):204–205.

Anestrus and Spontaneous Galactorrhea in a Hypothyroid Bitch

Brian C Buckrell, Walter H Johnson
PMCID: PMC1680249  PMID: 17422655

Abstract

A bitch, with a history of prolonged postweaning galactorrhea, dermatitis and lethargy, was examined because of an extended anestrus and the development of spontaneous galactorrhea. A diagnosis of hypothyroidism was made based on the history, a subnormal T4 level and the response to a therapeutic trial of thyroxine replacement. A possible pathogenesis for the spontaneous galactorrhea is discussed.

Keywords: Canine, hypothyroid, reproduction, galactorrhea, hyperprolactinemia

Full text

PDF
204

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Archer D. F. Physiology of prolactin. Clin Obstet Gynecol. 1980 Jun;23(2):325–335. doi: 10.1097/00003081-198006000-00005. [DOI] [PubMed] [Google Scholar]
  2. Baird D. T. Endocrinology of female infertility. Br Med Bull. 1979 May;35(2):193–198. doi: 10.1093/oxfordjournals.bmb.a071569. [DOI] [PubMed] [Google Scholar]
  3. Chastain C. B. Canine hypothyroidism. J Am Vet Med Assoc. 1982 Aug 15;181(4):349–353. [PubMed] [Google Scholar]
  4. De Coster R., Beckers J. F., Beerens D., De Mey J. A homologous radioimmunoassay for canine prolactin: plasma levels during the reproductive cycle. Acta Endocrinol (Copenh) 1983 Aug;103(4):473–478. doi: 10.1530/acta.0.1030473. [DOI] [PubMed] [Google Scholar]
  5. Evinger J. V., Nelson R. W. The clinical pharmacology of thyroid hormones in the dog. J Am Vet Med Assoc. 1984 Aug 1;185(3):314–316. [PubMed] [Google Scholar]
  6. Gräf K. J. Serum oestrogen, progesterone and prolactin concentrations in cyclic, pregnant and lactating beagle dogs. J Reprod Fertil. 1978 Jan;52(1):9–14. doi: 10.1530/jrf.0.0520009. [DOI] [PubMed] [Google Scholar]
  7. McNeilly A. S., Glasier A., Jonassen J., Howie P. W. Evidence for direct inhibition of ovarian function by prolactin. J Reprod Fertil. 1982 Jul;65(2):559–569. doi: 10.1530/jrf.0.0650559. [DOI] [PubMed] [Google Scholar]
  8. McNeilly A. S. Prolactin and the control of gonadotrophin secretion in the female. J Reprod Fertil. 1980 Mar;58(2):537–549. doi: 10.1530/jrf.0.0580537. [DOI] [PubMed] [Google Scholar]
  9. Nesbitt G. H., Izzo J., Peterson L., Wilkins R. J. Canine hypothyroidism: a retrospective study of 108 cases. J Am Vet Med Assoc. 1980 Dec 1;177(11):1117–1122. [PubMed] [Google Scholar]

Articles from The Canadian Veterinary Journal are provided here courtesy of Canadian Veterinary Medical Association

RESOURCES