Skip to main content

Some NLM-NCBI services and products are experiencing heavy traffic, which may affect performance and availability. We apologize for the inconvenience and appreciate your patience. For assistance, please contact our Help Desk at info@ncbi.nlm.nih.gov.

American Journal of Human Genetics logoLink to American Journal of Human Genetics
letter
. 1993 Jul;53(1):289–292.

Reevaluation of the linkage of an optic atrophy susceptibility gene to X-chromosomal markers in Finnish families with Leber hereditary optic neuroretinopathy (LHON)

V Juvonen, J Vilkki, P Aula, E Nikoskelainen, M L Savontaus
PMCID: PMC1682246  PMID: 8317495

Full text

PDF
289

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Black G. C., Chen Z. Y., Craig I. W., Powell J. F. Dinucleotide repeat polymorphism at the MAOA locus. Nucleic Acids Res. 1991 Feb 11;19(3):689–689. doi: 10.1093/nar/19.3.689-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bu X. D., Rotter J. I. X chromosome-linked and mitochondrial gene control of Leber hereditary optic neuropathy: evidence from segregation analysis for dependence on X chromosome inactivation. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):8198–8202. doi: 10.1073/pnas.88.18.8198. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Carvalho M. R., Müller B., Rötzer E., Berninger T., Kommerell G., Blankenagel A., Savontaus M. L., Meitinger T., Lorenz B. Leber's hereditary optic neuroretinopathy and the X-chromosomal susceptibility factor: no linkage to DXs7. Hum Hered. 1992;42(5):316–320. doi: 10.1159/000154089. [DOI] [PubMed] [Google Scholar]
  4. Chen J. D., Cox I., Denton M. J. Preliminary exclusion of an X-linked gene in Leber optic atrophy by linkage analysis. Hum Genet. 1989 Jun;82(3):203–207. doi: 10.1007/BF00291154. [DOI] [PubMed] [Google Scholar]
  5. Chen J. D., Denton M. J. X-chromosomal gene in Leber hereditary optic neuroretinopathy. Am J Hum Genet. 1991 Sep;49(3):692–693. [PMC free article] [PubMed] [Google Scholar]
  6. Holt I. J., Miller D. H., Harding A. E. Genetic heterogeneity and mitochondrial DNA heteroplasmy in Leber's hereditary optic neuropathy. J Med Genet. 1989 Dec;26(12):739–743. doi: 10.1136/jmg.26.12.739. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Howell N., Bindoff L. A., McCullough D. A., Kubacka I., Poulton J., Mackey D., Taylor L., Turnbull D. M. Leber hereditary optic neuropathy: identification of the same mitochondrial ND1 mutation in six pedigrees. Am J Hum Genet. 1991 Nov;49(5):939–950. [PMC free article] [PubMed] [Google Scholar]
  8. Huoponen K., Vilkki J., Aula P., Nikoskelainen E. K., Savontaus M. L. A new mtDNA mutation associated with Leber hereditary optic neuroretinopathy. Am J Hum Genet. 1991 Jun;48(6):1147–1153. [PMC free article] [PubMed] [Google Scholar]
  9. Konradi C., Ozelius L., Breakefield X. O. Highly polymorphic (GT)n repeat sequence in intron II of the human MAOB gene. Genomics. 1992 Jan;12(1):176–177. doi: 10.1016/0888-7543(92)90426-s. [DOI] [PubMed] [Google Scholar]
  10. Lathrop G. M., Lalouel J. M., Julier C., Ott J. Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci U S A. 1984 Jun;81(11):3443–3446. doi: 10.1073/pnas.81.11.3443. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Nikoskelainen E. K., Savontaus M. L., Wanne O. P., Katila M. J., Nummelin K. U. Leber's hereditary optic neuroretinopathy, a maternally inherited disease. A genealogic study in four pedigrees. Arch Ophthalmol. 1987 May;105(5):665–671. doi: 10.1001/archopht.1987.01060050083043. [DOI] [PubMed] [Google Scholar]
  12. Sweeney M. G., Davis M. B., Lashwood A., Brockington M., Toscano A., Harding A. E. Evidence against an X-linked locus close to DXS7 determining visual loss susceptibility in British and Italian families with Leber hereditary optic neuropathy. Am J Hum Genet. 1992 Oct;51(4):741–748. [PMC free article] [PubMed] [Google Scholar]
  13. Vilkki J., Ott J., Savontaus M. L., Aula P., Nikoskelainen E. K. Optic atrophy in Leber hereditary optic neuroretinopathy is probably determined by an X-chromosomal gene closely linked to DXS7. Am J Hum Genet. 1991 Mar;48(3):486–491. [PMC free article] [PubMed] [Google Scholar]
  14. Vilkki J., Savontaus M. L., Nikoskelainen E. K. Segregation of mitochondrial genomes in a heteroplasmic lineage with Leber hereditary optic neuroretinopathy. Am J Hum Genet. 1990 Jul;47(1):95–100. [PMC free article] [PubMed] [Google Scholar]
  15. Wallace D. C., Singh G., Lott M. T., Hodge J. A., Schurr T. G., Lezza A. M., Elsas L. J., 2nd, Nikoskelainen E. K. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science. 1988 Dec 9;242(4884):1427–1430. doi: 10.1126/science.3201231. [DOI] [PubMed] [Google Scholar]

Articles from American Journal of Human Genetics are provided here courtesy of American Society of Human Genetics

RESOURCES