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. 1990 Mar;46(3):587–590.

Maternal serum alpha-fetoprotein (MSAFP) patient-specific risk reporting: its use and misuse.

J N Macri 1, R V Kasturi 1, D A Krantz 1, E J Cook 1, J W Larsen 1
PMCID: PMC1683609  PMID: 1689955

Abstract

Fundamental to maternal serum alpha-fetoprotein screening is the clinical utility of the laboratory report. It follows that the scientific form of expression in that report is vital. Professional societies concur that patient-specific risk reporting is the preferred form. However, some intermediate steps being taken to calculate patient-specific risks are invalid because of the erroneous assumption that multiples of the median (MoMs) represent an interlaboratory common currency. The numerous methods by which MoMs may be calculated belie the foregoing assumption.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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