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. 1987 Oct;41(4):524–531.

Spinocerebellar ataxia: localization of an autosomal dominant locus between two markers on human chromosome 6.

S S Rich 1, P Wilkie 1, L Schut 1, G Vance 1, H T Orr 1
PMCID: PMC1684306  PMID: 3477955

Abstract

Inherited spinocerebellar ataxias (SCA) are progressively degenerative neurological diseases. The primary site of degeneration is the cerebellar cortex--in particular, the Purkinje cells. In the present report, the SCA locus, inherited as an autosomal dominant trait in a large kindred, is localized to a region approximately 15 centimorgans telomeric of HLA-A on the short arm of chromosome 6.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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