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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1987 Oct;41(4):517–523.

A genetical model for emergenesis: in memory of Laurence H. Snyder, 1901-86.

C C Li 1
PMCID: PMC1684313  PMID: 3661558

Abstract

When a phenotype is determined by a specific gene combination of several loci, it is called an emergenic trait. Such a trait, although genetically controlled, does not usually run in families, since the specific gene combination can hardly be preserved in the process of reproduction. The present paper suggests a concrete genetical model to account for the phenomenon that there is little resemblance between siblings and parent-child pairs with respect to this trait. The genetical model is multiple homozygosis for all loci involved in the gene configuration. The properties of such a trait in a random mating population for all families, as well as for the segregating families only, are investigated. Some of the difficulties in estimating the genetical parameters on the basis of empirical data are also discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. LI C. C. Some general properties of recessive inheritance. Am J Hum Genet. 1953 Sep;5(3):269–279. [PMC free article] [PubMed] [Google Scholar]
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