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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1987 Dec;41(6):1048–1060.

cDNA cloning and chromosomal localization (4q11-13) of a gene for statherin, a regulator of calcium in saliva.

L M Sabatini 1, L R Carlock 1, G W Johnson 1, E A Azen 1
PMCID: PMC1684366  PMID: 3502720

Abstract

On the basis of the known amino acid sequence of statherin, a human salivary protein, mixed synthetic oligonucleotides were synthesized and used to screen a cDNA library constructed from human parotid-gland mRNA. A cDNA clone coding for statherin was isolated from this library and has been completely sequenced. The cDNA represents a full-length (or nearly full-length) copy of an approximately 640-bp statherin mRNA. Statherin appears to be coded by a single-copy gene that maps to chromosome 4q11-4q13 when somatic-cell hybrids are used.

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Selected References

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