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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1984 May;36(3):646–654.

Genetic polymorphism of thyroxin-binding globulin (TBG) in the Pacific area.

M I Kamboh, C Kirwood
PMCID: PMC1684445  PMID: 6428221

Abstract

Human plasma samples, radiolabeled with [125I]thyroxin, from the Asian, Pacific, and Australian area have been subjected to isoelectric focusing to reveal genetic variation in thyroxin-binding globulin (TBG). A genetically determined electrophoretic slow variant, TBG S, indistinguishable from the variant found in black Africans, has been observed with a frequency of 1%-10% in all Melanesian and Polynesian populations studied. The TBG S variant is present also with low frequency in Micronesians and in some Indonesian populations. However, East Asians, Indians, and Australian Aborigines were found to be monomorphic.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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