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. 1984 May;36(3):601–612.

Identification of genetic variants in erythrocyte lysate by two-dimensional gel electrophoresis.

B B Rosenblum, J V Neel, S M Hanash, J L Joseph, N Yew
PMCID: PMC1684473  PMID: 6203403

Abstract

Two-dimensional gel electrophoresis followed by silver-staining has been employed to study 27 red cell lysates for genetic variation. Forty-six polypeptides selected without respect to variability were considered suitable for scoring. Only 23 of the total of 1,242 polypeptides could not be scored unambiguously. Of the remaining 1,219 polypeptides, 38 exhibited the combination of a normal and a variant polypeptide. All variants were present in either the father or the mother of the subjects. The observed index of heterozygosity was 3.1% +/- 0.5%.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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