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. 1985 Sep;37(5):922–930.

Improved resolution of PI (alpha 1-antitrypsin) phenotypes by a large-scale immobilized pH gradient.

A Görg, W Postel, J Weser, W Patutschnick, H Cleve
PMCID: PMC1684691  PMID: 3876767

Abstract

PI variants and PI M subtypes were examined by isoelectric focusing in a preformed immobilized pH gradient. Conditions were found that permit reliable classification of PI variants and of most PI M subtypes: the pH gradient ranges from 4.3 to 4.8 on a polyacrylamide gel with a length of 20 cm and a separation distance of approximately 16-17 cm (delta pH = 0.025 U/cm). The PI phenotypes observed are presented.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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