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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1976 Mar;28(2):167–173.

Application of the lod method to the detection of linkage between a quantitative trait and a qualitative marker: a simulation experiment.

K Lange, M A Spence, M B Frank
PMCID: PMC1684928  PMID: 1266848

Abstract

Simulation experiments were performed to assess the power of the lod method for detecting linkage between a quantitative trait and a qualitative marker. Using family data on the Amy2-Duffy linkage, it was found that linkage detection is feasible in certain limited circumstances. The same qualitative data yielded no evidence for a significant difference in male and female recombination fractions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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