Skip to main content
American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1990 Feb;46(2):383–392.

Interethnic genetic differentiation: GM polymorphism in eastern Senegal.

M Blanc 1, A Sanchez-Mazas 1, N H Van Blyenburgh 1, A Sevin 1, G Pison 1, A Langaney 1
PMCID: PMC1684972  PMID: 2105642

Abstract

Analysis of GM polymorphism has been performed on 1,806 individuals representing three sympatric ethnic groups--Bedik, Fulani, and Mandenkalu--of eastern Senegal. Haplotype frequencies estimated by maximum likelihood have been used to compute common genetic pools between the three samples and a number of other sub-Saharan African populations. Despite extreme linguistic and sociocultural differentiations and very high levels of endogamy, especially in the Bedik and Niokholo Mandenkalu, the three populations share about 90%-95% of their haplotype frequencies in a system which commonly provides strong genetic differentiations. This supports the view that, despite its importance at a large continental scale level, as it is discussed for a set of populations from many regions of sub-Saharan Africa, sociocultural differentiation usually has little effect on local genetic diversity.

Full text

PDF
383

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ai Q., Yuan Y., Zhao H., Li S., Du R. Distribution of red cell blood group systems in Yi, Tibetan and Manchu ethnic groups in China. Gene Geogr. 1987 Dec;1(3):169–176. [PubMed] [Google Scholar]
  2. Bouloux C., Gomila J., Langaney A. Hemotypology of the Bedik. Hum Biol. 1972 May;44(2):289–302. [PubMed] [Google Scholar]
  3. Cavalli-Sforza L. L., Zonta L. A., Nuzzo F., Bernini L., de Jong W. W., Meera Khan P., Ray A. K., Went L. N., Siniscalco M., Nijenhuis L. E. Studies on African Pygmies. I. A pilot investigation of Babinga Pygmies in the Central African Republic (with an analysis of genetic distances). Am J Hum Genet. 1969 May;21(3):252–274. [PMC free article] [PubMed] [Google Scholar]
  4. Hiernaux J. Blood polymorphism frequencies in the Sara Majingay of Chad. Ann Hum Biol. 1976 Mar;3(2):127–140. doi: 10.1080/03014467600001241. [DOI] [PubMed] [Google Scholar]
  5. Jenkins T., Zoutendyk A., Steinberg A. G. Gammaglobulin groups (Gm and Inv) of various Southern African populations. Am J Phys Anthropol. 1970 Mar;32(2):197–218. doi: 10.1002/ajpa.1330320206. [DOI] [PubMed] [Google Scholar]
  6. Langaney A., Gomila J. Bedik and Niokholonko intra and inter-ethnic migration. Hum Biol. 1973 May;45(2):137–150. [PubMed] [Google Scholar]
  7. Langaney A., Gomila J., Bouloux C. Bedik: bioassay of kinship. Hum Biol. 1972 Sep;44(3):475–488. [PubMed] [Google Scholar]
  8. Langaney A., Nadot R. Détection automatique des anomalies de transmission génétique. Ann Genet. 1973 Dec;16(4):247–253. [PubMed] [Google Scholar]
  9. Lefranc G., Rivat L., Serre J. L., Lalouel J. M., Pison G., Loiselet J., Ropartz C., de Lange G., van Loghem E. Common and uncommon immunoglobulin haplotypes among Lebanese communities. Hum Genet. 1978 Mar 17;41(2):197–209. doi: 10.1007/BF00273102. [DOI] [PubMed] [Google Scholar]
  10. Matsumoto H. Characteristics of Mongoloid and neighboring populations based on the genetic markers of human immunoglobulins. Hum Genet. 1988 Nov;80(3):207–218. doi: 10.1007/BF01790088. [DOI] [PubMed] [Google Scholar]
  11. Menozzi P., Piazza A., Cavalli-Sforza L. Synthetic maps of human gene frequencies in Europeans. Science. 1978 Sep 1;201(4358):786–792. doi: 10.1126/science.356262. [DOI] [PubMed] [Google Scholar]
  12. Morton N. E., Lalouel J. M. Bioassay of kinship in Micronesia. Am J Phys Anthropol. 1973 May;38(3):709–719. doi: 10.1002/ajpa.1330380309. [DOI] [PubMed] [Google Scholar]
  13. Neel J. V., Gershowitz H., Mohrenweiser H. W., Amos B., Kostyu D. D., Salzano F. M., Mestriner M. A., Lawrence D., Simões A. L., Smouse P. E. Genetic studies on the Ticuna, an enigmatic tribe of Central Amazonas. Ann Hum Genet. 1980 Jul;44(Pt 1):37–54. doi: 10.1111/j.1469-1809.1980.tb00944.x. [DOI] [PubMed] [Google Scholar]
  14. Sanchez-Mazas A., Langaney A. Common genetic pools between human populations. Hum Genet. 1988 Feb;78(2):161–166. doi: 10.1007/BF00278189. [DOI] [PubMed] [Google Scholar]
  15. Sokal R. R., Oden N. L., Thomson B. A. Genetic changes across language boundaries in Europe. Am J Phys Anthropol. 1988 Jul;76(3):337–361. doi: 10.1002/ajpa.1330760308. [DOI] [PubMed] [Google Scholar]
  16. Steinberg A. G. Gm and Inv allotypes of some Sidamo Ethiopians. Am J Phys Anthropol. 1973 Nov;39(3):403–408. doi: 10.1002/ajpa.1330390308. [DOI] [PubMed] [Google Scholar]
  17. Steinberg A. G., Jenkins T., Nurse G. T., Harpending H. C. Gammaglobulin groups of the Khoisan peoples of Southern Africa: evidence for polymorphism for a Gm1,5,13,14,21 haplotype among the San. Am J Hum Genet. 1975 Jul;27(4):528–542. [PMC free article] [PubMed] [Google Scholar]
  18. van Loghem E., Salimonu L., Williams A. I., Osunkoya B. O., Boyd A. M., de Lange G., Nijenhuis L. E. Immunoglobulin allotypes in African populations. I. Gm--Am haplotypes in a Nigerian population. J Immunogenet. 1978 Jun;5(3):143–147. doi: 10.1111/j.1744-313x.1978.tb00639.x. [DOI] [PubMed] [Google Scholar]

Articles from American Journal of Human Genetics are provided here courtesy of American Society of Human Genetics

RESOURCES