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. 1990 Feb;46(2):340–349.

Three genes for enzymes of the pyruvate dehydrogenase complex map to human chromosomes 3, 7, and X.

S Olson 1, B J Song 1, T L Huh 1, Y T Chi 1, R L Veech 1, O W McBride 1
PMCID: PMC1684992  PMID: 1967901

Abstract

The genes for three proteins of the pyruvate dehydrogenase (PDH) complex have been assigned to human chromosomes by Southern analysis of a panel of human-rodent somatic cell hybrid DNAs with cDNA probes for these genes. PDH-E1 alpha has been localized on human chromosome 3p13-q23. The assignments of lipoamide dehydrogenase(E3) and PDH-E1 alpha [corrected] to chromosomes 7 and Xp, respectively, have been confirmed. Restrictive-fragment-length polymorphisms have been identified with E3, which will permit further localization of this gene by genetic linkage analysis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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