Abstract
A large pericentric inversion, inv(8) (p11q24), was ascertained in a male investigated because his wife had had repeated miscarriages. The inversion segregated in 3 generations of the family, and no chromosomally unbalanced offspring were detected. The miscarriage and the inversion could not be causally related.
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- Betz A., Turleau C., de Grouchy J. Hétérozygotie et homozygotie pour une inversion péricentrique du 3 humain. Ann Genet. 1974 Jun;17(2):79–80. [PubMed] [Google Scholar]
- Bhasin M. K., Foerster W., Fuhrmann W. A cytogenetic study of recurrent abortion. Humangenetik. 1973 Apr 16;18(2):139–148. doi: 10.1007/BF00291481. [DOI] [PubMed] [Google Scholar]
- Breg W. R., Alderdice P. W., Miller D. A., Miller O. J. Quinacrine fluorescence patterns and terminal DNA labelling of human C group chromosomes. Nat New Biol. 1972 Mar 22;236(64):76–78. doi: 10.1038/newbio236076a0. [DOI] [PubMed] [Google Scholar]
- Caspersson T., Zech L., Johansson C., Modest E. J. Identification of human chromosomes by DNA-binding fluorescent agents. Chromosoma. 1970;30(2):215–227. doi: 10.1007/BF00282002. [DOI] [PubMed] [Google Scholar]
- De la Chapelle A., Schröder J., Kokkonen J. Cytogenetics of recurrent abortion or unsuccessful pregnancy. Int J Fertil. 1973;18(4):215–219. [PubMed] [Google Scholar]
- Fujimoto A., Wilson M. G., Towner J. W. Familial inversion of chromosome No. 8: an affected child and a carrier fetus. Humangenetik. 1975;27(1):67–73. [PubMed] [Google Scholar]
- Jacobs P. A., Buckton K. E., Cunningham C., Newton M. An analysis of the break points of structural rearrangements in man. J Med Genet. 1974 Mar;11(1):50–64. doi: 10.1136/jmg.11.1.50. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jacobs P. A., Cruickshank G., Faed M. J., Frackiewicz A., Robson E. B., Harris H., Sutherland I. Pericentric inversion of a group C autosome: a study of three families. Ann Hum Genet. 1968 Jan;31(3):219–230. doi: 10.1111/j.1469-1809.1968.tb00552.x. [DOI] [PubMed] [Google Scholar]
- Järvinen P. A., Kokkonen J. Etiology and treatment of failed pregnancies. Int J Fertil. 1972;17(2):81–85. [PubMed] [Google Scholar]
- Leonard C., Hazael-Massieux P., Bocquet L., Larget-Piet L., Boué J. Inversion péricentrique inv (2) (p11 q13) dans des familles non apparentées. Humangenetik. 1975 Jun 19;28(2):121–128. doi: 10.1007/BF00735744. [DOI] [PubMed] [Google Scholar]
- McKenzie W. H., Lubs H. A. Human Q and C chromosomal variations: distribution and incidence. Cytogenet Cell Genet. 1975;14(2):97–115. doi: 10.1159/000130330. [DOI] [PubMed] [Google Scholar]
- Seabright M. A rapid banding technique for human chromosomes. Lancet. 1971 Oct 30;2(7731):971–972. doi: 10.1016/s0140-6736(71)90287-x. [DOI] [PubMed] [Google Scholar]
- de la Chapelle A., Schröder J., Stenstrand K., Fellman J., Herva R., Saarni M., Anttolainen I., Tallila I., Tervilä L., Husa L. Pericentric inversions of human chromosomes 9 and 10. Am J Hum Genet. 1974 Nov;26(6):746–766. [PMC free article] [PubMed] [Google Scholar]

