Abstract
Fluctuating asymmetry for the palmar atd angle was studied in propositi born with CL(P) and their normal parents and sibs. The propositi with a family history of this congenital malformation were significantly different from the controls for this type of asymmetry. The propositi without a family history and the normal parents and sibs of both types of propositi were similar to the controls. The difference between the two types of propositi suggests that in some individuals a genetic mechanism may account for CL(P) and increased fluctuating asymmetry for this dermatoglyphic trait.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Aase J. M., Lyons R. B. Technique for recording dermatoglyphics. Lancet. 1971 Feb 27;1(7696):432–433. doi: 10.1016/s0140-6736(71)92417-2. [DOI] [PubMed] [Google Scholar]
- Adams M. S., Niswander J. D. Developmental 'noise' and a congenital malformation. Genet Res. 1967 Dec;10(3):313–317. doi: 10.1017/s0016672300011071. [DOI] [PubMed] [Google Scholar]
- Carter C. O. Genetics of common disorders. Br Med Bull. 1969 Jan;25(1):52–57. doi: 10.1093/oxfordjournals.bmb.a070671. [DOI] [PubMed] [Google Scholar]
- LUBS H. A., Jr, KOENIG E. U., BRANDT I. K. Trisomy 13-15: a clinical syndrome. Lancet. 1961 Nov 4;2(7210):1001–1002. doi: 10.1016/s0140-6736(61)90963-1. [DOI] [PubMed] [Google Scholar]
- NEEL J. V. A study of major congenital defects in Japanese infants. Am J Hum Genet. 1958 Dec;10(4):398–445. [PMC free article] [PubMed] [Google Scholar]
- VAN DER WOUDE A. Fistula labii inferioris congenita and its association with cleft lip and palate. Am J Hum Genet. 1954 Jun;6(2):244–256. [PMC free article] [PubMed] [Google Scholar]
- WOOLF C. M., WOOLF R. M., BROADBENT T. R. A genetic study of cleft lip and palate in Utah. Am J Hum Genet. 1963 Jun;15:209–215. [PMC free article] [PubMed] [Google Scholar]
- Woolf C. M. Congenital cleft lip. A genetic study of 496 propositi. J Med Genet. 1971 Mar;8(1):65–83. doi: 10.1136/jmg.8.1.65. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Woolf C. M., Woolf R. M., Broadbent T. R. Cleft lip and palate in parent and child. Plast Reconstr Surg. 1969 Nov;44(5):436–440. [PubMed] [Google Scholar]