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. 1981 Sep;33(5):745–751.

Unstable familial translocations: A t(11;22)mat inherited as a t(11;15).

D J Tomkins
PMCID: PMC1685141  PMID: 7294023

Abstract

Unusual inheritance of a reciprocal translocation, t(11;22)(p11;p12)mat was discovered in a family with one daughter having a different translocation, t(11;15)(p11;p12). Another daughter inherited the same translocation as her mother. The breakpoints through the nucleolar organizing regions (NORs) of chromosomes 15 and 22 were determined by silver staining. A review of the literature has demonstrated that such unstable familial translocations are very rare and can occur either in mitosis or meiosis. They usually involve exchanges between centromeres, telomeres, or NORs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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