Skip to main content
NCBI home page
American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1977 Sep;29(5):419–430.

Two more "private" polymorphisms of Amerindian tribes: LDHb GUA-1 and ACP1 B GUA-1 in the Guaymi in Panama.

R J Tanis, J V Neel, R Torres de Arauz
PMCID: PMC1685407  PMID: 900121

Abstract

A survey of Guaymi Indians of Panama for the occurrence of genetic variants of 25 proteins of the erythrocytes and sera have revealed, in addition to seven well-known genetic polymorphisms, four rare variants and two "private polymorphisms," the latter involving erythrocyte acid phosphatase and lactate dehydrogenase. The significance of such private polymorphisms in tribal populations to the interpretation of rare variants in civilized populations is emphasized.

Full text

PDF
419

Images in this article

422p422-a
on p.422

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARENDS T., GALLANGO M. L. TRANSFERRINS IN VENEZUELAN INDIANS: HIGH FREQUENCY OF A SLOW-MOVING VARIANT. Science. 1964 Jan 24;143(3604):367–368. doi: 10.1126/science.143.3604.367. [DOI] [PubMed] [Google Scholar]
  2. BEUTLER E., BALUDA M. C., STURGEON P., DAY R. A NEW GENETIC ABNORMALITY RESULTING IN GALACTOSE-1-PHOSPHATE URIDYLTRANSFERASE DEFICIENCY. Lancet. 1965 Feb 13;1(7381):353–354. doi: 10.1016/s0140-6736(65)91782-4. [DOI] [PubMed] [Google Scholar]
  3. Beutler E., Baluda M. C., Sturgeon P., Day R. W. The genetics of galactose-1-phosphate uridyl transferase deficiency. J Lab Clin Med. 1966 Oct;68(4):646–658. [PubMed] [Google Scholar]
  4. Hopkinson D. A., Mestriner M. A., Cortner J., Harris H. Esterase D: a new human polymorphism. Ann Hum Genet. 1973 Oct;37(2):119–137. doi: 10.1111/j.1469-1809.1973.tb01820.x. [DOI] [PubMed] [Google Scholar]
  5. Kitamura M., Iijima N., Hashimoto F., Hiratsuka A. Hereditary deficiency of subunit H of lactate dehydrogenase. Clin Chim Acta. 1971 Oct;34(3):419–423. doi: 10.1016/0009-8981(71)90095-7. [DOI] [PubMed] [Google Scholar]
  6. Matson G. A., Sutton H. E., Swanson J., Robinson A. R. Distribution of haptoglobin, transferrin, and hemoglobin types among Indians of Middle America: in British Honduras, Costa Rica and Panama. Am J Phys Anthropol. 1965 Jun;23(2):123–129. doi: 10.1002/ajpa.1330230211. [DOI] [PubMed] [Google Scholar]
  7. Matson G. A., Swanson J. Distribution of hereditary blood antigens among Indians in Middle America. 8. In Panama. Am J Phys Anthropol. 1965 Dec;23(4):413–426. doi: 10.1002/ajpa.1330230416. [DOI] [PubMed] [Google Scholar]
  8. Mestriner M. A., Salzano F. M., Neel J. V., Ayres M. Esterase D in South American Indians. Am J Hum Genet. 1976 May;28(3):257–261. [PMC free article] [PubMed] [Google Scholar]
  9. Moore M. J., Funakoshi S., Deutsch H. F. Human carbonic anhydrases. VII. A new C type isozyme in erythrocytes of American Negroes. Biochem Genet. 1971 Dec;5(6):497–504. doi: 10.1007/BF00485667. [DOI] [PubMed] [Google Scholar]
  10. NEEL J. V., SALZANO F. M. A PROSPECTUS FOR GENETIC STUDIES FOF THE AMERICAN INDIAN. Cold Spring Harb Symp Quant Biol. 1964;29:85–98. doi: 10.1101/sqb.1964.029.01.014. [DOI] [PubMed] [Google Scholar]
  11. Neel J. V. "Private" genetic variants and the frequency of mutation among South American Indians. Proc Natl Acad Sci U S A. 1973 Dec;70(12):3311–3315. doi: 10.1073/pnas.70.12.3311. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Neel J. V., Ferrell R. E., Conard R. A. The frequency of "rare" protein variants in Marshall islanders and other Micronesians. Am J Hum Genet. 1976 May;28(3):262–269. [PMC free article] [PubMed] [Google Scholar]
  13. Neel J. V., Tanis R. J., Migliazza E. C., Spielman R. S., Salzano F., Oliver W. J., Morrow M., Bachofer S. Genetic studies of the Macushi and Wapishana Indians. I. Rare genetic variants and a "private polymorphism' of esterase A. Hum Genet. 1977 Apr 7;36(1):81–107. doi: 10.1007/BF00390440. [DOI] [PubMed] [Google Scholar]
  14. PARKER W. C., BEARN A. G. Haptoglobin and transferrin variation in humans and primates: two new transferrins in Chinese and Japanese populations. Ann Hum Genet. 1961 Dec;25:227–241. doi: 10.1111/j.1469-1809.1962.tb01523.x. [DOI] [PubMed] [Google Scholar]
  15. Pastewka J. V., Reed R. A., Ness A. T., Peacock A. C. An improved haptoglobin subtyping procedure using polyacrylamide gel electrophoresis. Haptoglobin gene frequency distribution among a group of blood bank donors. Anal Biochem. 1973 Jan;51(1):152–162. doi: 10.1016/0003-2697(73)90463-6. [DOI] [PubMed] [Google Scholar]
  16. SMITHIES O., CONNELL G. E., DIXON G. H. Chromosomal rearrangements and the evolution of haptoglobin genes. Nature. 1962 Oct 20;196:232–236. doi: 10.1038/196232a0. [DOI] [PubMed] [Google Scholar]
  17. SMITHIES O. Third allele at the serum beta-globulin locus in humans. Nature. 1958 Apr 26;181(4617):1203–1204. doi: 10.1038/1811203b0. [DOI] [PubMed] [Google Scholar]
  18. SPENCER N., HOPKINSON D. A., HARRIS H. PHOSPHOGLUCOMUTASE POLYMORPHISM IN MAN. Nature. 1964 Nov 21;204:742–745. doi: 10.1038/204742a0. [DOI] [PubMed] [Google Scholar]
  19. Swallow D. M., Povey S., Harris H. Activity of the "red cell" acid phosphatase locus in other tissues. Ann Hum Genet. 1973 Jul;37(1):31–38. doi: 10.1111/j.1469-1809.1973.tb01812.x. [DOI] [PubMed] [Google Scholar]
  20. Tanis R. J., Neel J. V., Dovey H., Morrow M. The genetic structure of a tribal population, the Yanomama Indians. IX. Gene frequencies for 18 serum protein and erythrocyte enzyme systems in the Yanomama and five neighboring tribes: nine new variants. Am J Hum Genet. 1973 Nov;25(6):655–676. [PMC free article] [PubMed] [Google Scholar]
  21. Tanis R., Ferrell R. E., Nell J. V., Morrow M. Albumin Yanomama-2, a 'private' polymorphism of serum albumin. Ann Hum Genet. 1974 Oct;38(2):179–190. doi: 10.1111/j.1469-1809.1974.tb01949.x. [DOI] [PubMed] [Google Scholar]
  22. Thymann M., Henningsen K. Haptoglobin type Hp-Jo and hypohaptoglobinaemia in a Danish family. Preliminary report. Hum Hered. 1975;25(6):501–505. doi: 10.1159/000152766. [DOI] [PubMed] [Google Scholar]
  23. Tiffany T. O., Jansen J. M., Burtis C. A., Overton J. B., Scott C. D. Enzymatic kinetic rate and end-point analyses of substrate, by use of a GeMSAEC fast analyzer. Clin Chem. 1972 Aug;18(8):829–840. [PubMed] [Google Scholar]
  24. Ward R. H., Gershowitz H., Layrisse M., Neel J. V. The genetic structure of a tribal population, the Yanomama Indians XI. Gene frequencies for 10 blood groups and the ABH-Le secretor traits in the Yanomama and their neighbors; the uniqueness of the tribe. Am J Hum Genet. 1975 Jan;27(1):1–30. [PMC free article] [PubMed] [Google Scholar]

Articles from American Journal of Human Genetics are provided here courtesy of American Society of Human Genetics

RESOURCES