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American Journal of Human Genetics logoLink to American Journal of Human Genetics
letter
. 1982 Sep;34(5):811–817.

Genetic evidence for the inactivation of a human autosomal locus attached to an inactive X chromosome

T Mohandas, R S Sparkes, L J Shapiro
PMCID: PMC1685441  PMID: 7124733

Abstract

Mouse-human cell hybrid clones retaining an inactive translocated chromosome involving the human X and 13 were isolated. Esterase D, a marker on the segment of chromosome 13 translocated to the X, was not expressed in these clones. These results provide genetic evidence for the spreading of inactivation into the autosomal segment in an inactive human X-autosome translocation.

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Selected References

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