Abstract
Our field is in a rapid state of evolution. The broader concerns of human genetics not of immediate medical interest such as behavioral genetics are often investigated by persons not trained or identified as human geneticists. Both medical genetics and human genetics in general have prospered when various biologic techniques have been applied to genetic concepts. A search for novel biologic methods may provide new insights and may bridge the gulf between Mendelian and biometric approaches in studies of behavior and of common diseases. Medical geneticists need to broaden their fields of interest to encompass other fields than those of pediatric interest alone. We need to attract more basic scientists. Our field is evolving from a largely research oriented science to a service-oriented specialty. This logical development is a sign of increasing maturity and makes available to the public the results of our research. The resulting stresses and strains need careful watching to prevent their slowing the momentum of our science which can contribute continued insights into the many problems of behavior, health, and disease.
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Selected References
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- Childs B. Persistent echoes of the nature-nurture argument. Am J Hum Genet. 1977 Jan;29(1):1–13. [PMC free article] [PubMed] [Google Scholar]
- DUNN L. C. Cross currents in the history of human genetics. Am J Hum Genet. 1962 Mar;14:1–13. [PMC free article] [PubMed] [Google Scholar]
- Goldstein J. L., Schrott H. G., Hazzard W. R., Bierman E. L., Motulsky A. G. Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia. J Clin Invest. 1973 Jul;52(7):1544–1568. doi: 10.1172/JCI107332. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hamerton J. L. Human population cytogenetics: dilemmas and problems. Am J Hum Genet. 1976 Mar;28(2):107–122. [PMC free article] [PubMed] [Google Scholar]
- Lewontin R. C. Annotation: the analysis of variance and the analysis of causes. Am J Hum Genet. 1974 May;26(3):400–411. [PMC free article] [PubMed] [Google Scholar]
- MULLER H. J. Our load of mutations. Am J Hum Genet. 1950 Jun;2(2):111–176. [PMC free article] [PubMed] [Google Scholar]
- McKusick V. A. The growth and development of human genetics as a clinical discipline. Am J Hum Genet. 1975 May;27(3):261–273. [PMC free article] [PubMed] [Google Scholar]
- Neel J. V. Our twenty-fifth. Am J Hum Genet. 1974 Mar;26(2):136–144. [PMC free article] [PubMed] [Google Scholar]
- Neufeld E. F. The biochemical basis for mucopolysaccharidoses and mucolipidoses. Prog Med Genet. 1974;10:81–101. [PubMed] [Google Scholar]