Abstract
A study of the uridine monophosphate kinase (UMPK) electrophoretic patterns in Venezuelan individuals from the mestizo population of Caracas and from the Warao Indians of the Nabasanuka village in the Delta of the Orinoco River are reported. Among the mestizo population, the frequency of the UMPK1, UMPK2, and UMPK3 alleles was .979, .020, and .001, respectively. A higher frequency of the UMPK3 gene was seen in the highly inbred Warao Indians than any other population studied to date.
Full text
PDF



Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Arends T., Gallango M. L., Layrisse M., Wilbert J., Heinen H. D. Albumin Warao: new type of human alloalbuminemia. Blood. 1969 Mar;33(3):414–420. [PubMed] [Google Scholar]
- Fildes R. A., Harris H. Genetically determined variation of adenylate kinase in man. Nature. 1966 Jan 15;209(5020):261–263. doi: 10.1038/209261a0. [DOI] [PubMed] [Google Scholar]
- Giblett E. R., Anderson J. E., Chen S. H., Teng Y. S., Cohen F. Uridine monophosphate kinase: A new genetic polymorphism with possible clinical implications. Am J Hum Genet. 1974 Sep;26(5):627–635. [PMC free article] [PubMed] [Google Scholar]
- Giblett E. R., Anderson J. E., Lewis M., Kaita H. A new polymorphic enzyme, uridine monophosphate kinase: gene frequencies and a linkage analysis. Birth Defects Orig Artic Ser. 1975;11(3):159–161. [PubMed] [Google Scholar]
- Harada S., Ito M., Misawa S. Red cell uridine monophosphate kinase polymorphism in Japanese. Humangenetik. 1975 Sep 23;29(3):255–257. doi: 10.1007/BF00297632. [DOI] [PubMed] [Google Scholar]
- Kuhn B., Kömpf J., Ritter H. Red-cell uridine-5-monophosphate kinase (UMPK): formal genetics, linkage analysis and population genetics from southwestern Germany. Humangenetik. 1975 Jul 23;28(3):255–258. doi: 10.1007/BF00278554. [DOI] [PubMed] [Google Scholar]
- Satlin A., Kucherlapati R., Ruddle F. H. Assignment of the gene for human uridine monophosphate kinase to chromosome 1 using somatic cell hybrid clone panels. Cytogenet Cell Genet. 1975;15(3):146–152. doi: 10.1159/000130513. [DOI] [PubMed] [Google Scholar]
- Teng Y. S., Chen S. H., Scott C. R. Human erythrocyte pyrimidine nucleoside monophosphate kinase. Partial purification and properties of two allelic gene products. J Biol Chem. 1976 Jul 25;251(14):4179–4183. [PubMed] [Google Scholar]
- Teng Y., Chen S., Giblett E. R. Red cell uridine monophosphate kinase: effects of red cell aging on the activity of two UMPK gene products. Am J Hum Genet. 1976 Mar;28(2):138–142. [PMC free article] [PubMed] [Google Scholar]

