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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1978 May;30(3):283–292.

A note on the essential parameters of the two-allele autosomal locus model.

P M Fishman, T Reich, B Suarez, J W James
PMCID: PMC1685580  PMID: 677125

Abstract

A resolution of the parameter problem for the two-allele autosomal locus (TAAL) model has been presented. It was shown that three are four essential parameters which describe the model, by examination of the joint probability for sibs with specified parental phenotypes. This equation together with previously derived prevalence relationships uniquely specifices all parameters of the model except for the singular case VA = 0.

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Selected References

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