Abstract
Genetic variation of the B subunit of human coagulation factor XIII has been observed after electrophoresis of plasma or serum samples on thin layer agarose plates and subsequent immunofixation with a specific antiserum. The F-XIIIB locus is autosomal and has three alleles. In Australian blood donors, the F-XIIIB1, F-XIIIB2 and F-XIIIB3 alleles have frequencies of .747, .084, and .169, respectively.
Full text
PDF





Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Barbui T., Cartei G., Chisesi T., Dini E. Electroimmunoassay of plasma subunits-a and -s in a case of congenital fibrin stabilizing factor deficiency. Thromb Diath Haemorrh. 1974 Sep 30;32(1):124–131. [PubMed] [Google Scholar]
- Barbui T., Rodeghiero F., Dini E., Mariani G., Paa M. L., De Biasi R., Murillo R. C., Umana C. M. Subunits A and S inheritance in four families with congenital factor XIII deficiency. Br J Haematol. 1978 Feb;38(2):267–271. doi: 10.1111/j.1365-2141.1978.tb01042.x. [DOI] [PubMed] [Google Scholar]
- Board P. G. Genetic polymorphism of the A subunit of human coagulation factor XIII. Am J Hum Genet. 1979 Mar;31(2):116–124. [PMC free article] [PubMed] [Google Scholar]
- Girolami A., Burul A., Fabris F., Cappellato G., Betterle C. Studies on factor XIII antigen in congenital factor XIII deficiency. A tentative classification of the disease in two groups. Folia Haematol Int Mag Klin Morphol Blutforsch. 1978;105(1):131–141. [PubMed] [Google Scholar]
- Hampton J. W., Cunningham G. R., Bird R. M. The pattern of inheritance of defective fibrinase (Factor 13). J Lab Clin Med. 1966 Jun;67(6):914–921. [PubMed] [Google Scholar]
- Israels E. D., Paraskevas F., Israels L. G. Immunological studies of coagulation factor XIII. J Clin Invest. 1973 Oct;52(10):2398–2403. doi: 10.1172/JCI107429. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lorand L., Gray A. J., Brown K., Credo R. B., Curtis C. G., Domanik R. A., Stenberg P. Dissociation of the subunit structure of fibrin stabilizing factor during activation of the zymogen. Biochem Biophys Res Commun. 1974 Feb 27;56(4):914–922. doi: 10.1016/s0006-291x(74)80275-5. [DOI] [PubMed] [Google Scholar]
- Lorand L., Urayama T., Atencio A. C., Hsia D. Y. Inheritance of deficiency of fibrin-stabilizing factor (factor 13). Am J Hum Genet. 1970 Jan;22(1):89–95. [PMC free article] [PubMed] [Google Scholar]
- Losowsky M. S., Miloszewski K. J. Factor XIII. Br J Haematol. 1977 Sep;37(1):1–5. [PubMed] [Google Scholar]
- McDonagh J., McDonagh R. P., Jr, Duckert F. Genetic aspects of factor XIII deficiency. Ann Hum Genet. 1971 Oct;35(2):197–206. doi: 10.1111/j.1469-1809.1956.tb01392.x. [DOI] [PubMed] [Google Scholar]
- Ratnoff O. D., Steinberg A. G. Inheritance of fibrin-stabilising-factor deficiency. Lancet. 1968 Jan 6;1(7532):25–26. doi: 10.1016/s0140-6736(68)90012-3. [DOI] [PubMed] [Google Scholar]
- Schwartz M. L., Pizzo S. V., Hill R. L., McKee P. A. Human Factor XIII from plasma and platelets. Molecular weights, subunit structures, proteolytic activation, and cross-linking of fibrinogen and fibrin. J Biol Chem. 1973 Feb 25;248(4):1395–1407. [PubMed] [Google Scholar]