Skip to main content
NCBI home page
The Canadian Veterinary Journal logoLink to The Canadian Veterinary Journal
. 1994 Oct;35(10):617–621.

Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs.

D W Scott 1, W H Miller Jr 1, S M Cayatte 1, M S Bagladi 1
PMCID: PMC1686771  PMID: 7994702

Abstract

Tylosin tablets (20 mg/kg, q12h) were administered orally to 21 dogs with superficial or deep staphylococcal pyodermas. Response to therapy was excellent in 90.5% of the dogs, and in vitro susceptibility testing correlated perfectly with therapeutic response. Duration of therapy varied from 17 to 91 days, with an average of 33 days. Relapses occurred in 28.6% of the dogs within a three-month period. No side effects were reported. Under the conditions of the study, tylosin was an effective and safe antibiotic for the treatment of staphylococcal pyoderma in dogs.

Full text

PDF
617

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Angarano D. W., MacDonald J. M. Efficacy of cefadroxil in the treatment of bacterial dermatitis in dogs. J Am Vet Med Assoc. 1989 Jan 1;194(1):57–59. [PubMed] [Google Scholar]
  2. Burrows G. E. Pharmacotherapeutics of macrolides, lincomycins, and spectinomycin. J Am Vet Med Assoc. 1980 May 15;176(10 Spec No):1072–1077. [PubMed] [Google Scholar]
  3. Cannon R. W. Clinical evaluation of Tribrissen. New antibacterial agent for dogs and cats. Vet Med Small Anim Clin. 1976 Aug;71(8):1090–1091. [PubMed] [Google Scholar]
  4. Cox H. U., Hoskins J. D., Newman S. S., Foil C. S., Turnwald G. H., Roy A. F. Temporal study of staphylococcal species on healthy dogs. Am J Vet Res. 1988 Jun;49(6):747–751. [PubMed] [Google Scholar]
  5. Cox H. U., Hoskins J. D., Roy A. F., Newman S. S., Luther D. G. Antimicrobial susceptibility of coagulase-positive staphylococci isolated from Louisiana dogs. Am J Vet Res. 1984 Oct;45(10):2039–2042. [PubMed] [Google Scholar]
  6. Devriese L. A., Devos A. H., Van Damme L. R. Effect of feeding antibiotics on experimental Staphylococcus aureus colinization on the surface of chickens. Avian Dis. 1973 Jan-Mar;17(1):24–30. [PubMed] [Google Scholar]
  7. Devriese L. A. In vitro susceptibility and resistance of animal staphylococci to macrolide antibiotics and related compounds. Ann Rech Vet. 1976;7(1):65–74. [PubMed] [Google Scholar]
  8. Frank L. A., Kunkle G. A. Comparison of the efficacy of cefadroxil and generic and proprietary cephalexin in the treatment of pyoderma in dogs. J Am Vet Med Assoc. 1993 Aug 15;203(4):530–533. [PubMed] [Google Scholar]
  9. Jensen N. E. Experimental bovine group-B streptococcal mastitis induced by strains of human and bovine origin. Nord Vet Med. 1982 Dec;34(12):441–450. [PubMed] [Google Scholar]
  10. Kunkle G. A. New considerations for rational antibiotic therapy of cutaneous staphylococcal infection in the dog. Semin Vet Med Surg (Small Anim) 1987 Aug;2(3):212–220. [PubMed] [Google Scholar]
  11. Lacey R. W. Rarity of tylosin resistance in human pathogenic bacteria. Vet Rec. 1988 Apr 30;122(18):438–439. doi: 10.1136/vr.122.18.438. [DOI] [PubMed] [Google Scholar]
  12. Love D. N., Lomas G., Bailey M., Jones R. F., Weston I. Characterization of strains of Staphylococci from infections in dogs and cats. J Small Anim Pract. 1981 Apr;22(4):195–199. doi: 10.1111/j.1748-5827.1981.tb01405.x. [DOI] [PubMed] [Google Scholar]
  13. Matsuoka M., Endou K., Nakajima Y. Localization of a determinant mediating partial macrolide resistance in Staphylococcus aureus. Microbiol Immunol. 1990;34(8):643–652. doi: 10.1111/j.1348-0421.1990.tb01040.x. [DOI] [PubMed] [Google Scholar]
  14. Medleau L., Long R. E., Brown J., Miller W. H. Frequency and antimicrobial susceptibility of Staphylococcus species isolated from canine pyodermas. Am J Vet Res. 1986 Feb;47(2):229–231. [PubMed] [Google Scholar]
  15. Phillips W. E., Jr, Williams B. J. Antimicrobial susceptibility patterns of canine Staphylococcus intermedius isolates from veterinary clinical specimens. Am J Vet Res. 1984 Nov;45(11):2376–2379. [PubMed] [Google Scholar]
  16. Rhoades H. E. Sensitivity of bacteria to 16 antibiotic agents. Vet Med Small Anim Clin. 1979 Jul;74(7):976–979. [PubMed] [Google Scholar]
  17. Sampson G. R., Sauter R. A., Gregory R. P. Clinical appraisal of tylosin in dogs. Vet Med Small Anim Clin. 1974 Oct;69(10):1259–1262. [PubMed] [Google Scholar]
  18. Scott D. W., Paradis M. A survey of canine and feline skin disorders seen in a university practice: Small Animal Clinic, University of Montréal, Saint-Hyacinthe, Québec (1987-1988). Can Vet J. 1990 Dec;31(12):830–835. [PMC free article] [PubMed] [Google Scholar]
  19. Takahashi I., Yoshida T., Higashide Y., Sakano T. [Susceptibilities of Escherichia coli, Salmonella and Staphylococcus aureus isolated from animals to ofloxacin and commonly used antimicrobial agents]. Jpn J Antibiot. 1990 Jan;43(1):89–99. [PubMed] [Google Scholar]
  20. Woldehiwet Z., Jones J. J. Species distribution of coagulase-positive staphylococci isolated from dogs. Vet Rec. 1990 May 12;126(19):485–485. [PubMed] [Google Scholar]

Articles from The Canadian Veterinary Journal are provided here courtesy of Canadian Veterinary Medical Association

RESOURCES