Skip to main content
PMC home page
British Medical Journal logoLink to British Medical Journal
. 1976 Oct 2;2(6039):790–791. doi: 10.1136/bmj.2.6039.790

Meconium ileus equivalent in adults with cystic fibrosis of pancreas: a report of six cases.

M E Hodson, M B Mearns, J C Batten
PMCID: PMC1688637  PMID: 974611

Abstract

Eleven episodes of "meconium ileus equivalent" have been seen in six adults with cystic fibrosis of the pancreas. Three patients were initially treated surgically; one died and the other two developed serious postoperative chest infections. Six episodes were successfully treated medically with acetylcysteine orally and by enema, nasogastric suction, and intravenous fluids. Operation should be avoided if possible, and maintenance treatment with acetylcysteine may be necessary to prevent relapse.

Full text

PDF

Images in this article

791p791-a
on p.791

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DANILCZENKO A., DI SANT'AGNESE P. A., DISCHE Z. Physicochemical differences of mucoproteins in duodenal fluid of patients with cystic fibrosis of the pancreas and controls; clinical aspects. Pediatrics. 1957 Feb;19(2):252–260. [PubMed] [Google Scholar]
  2. Donnison A. B., Shwachman H., Gross R. E. A review of 164 children with meconium ileus seen at the Children's Hospital Medical Center, Boston. Pediatrics. 1966 May;37(5):833–850. [PubMed] [Google Scholar]
  3. FANCONI A. [Postneonatal meconium ileus in pancreatic cystic fibrosis]. Helv Paediatr Acta. 1960 Dec;15:566–579. [PubMed] [Google Scholar]
  4. GARNHAM J. R., CARTER T. R. MECHANICAL INTESTINAL OBSTRUCTION IN A YOUNG ADULT MALE WITH MUCOVISCIDOSIS. Gut. 1964 Jun;5:256–259. doi: 10.1136/gut.5.3.256. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gracey M., Burke V., Anderson C. M. Treatment of abdominal pain in cystic fibrosis by oral administration of n-acetyl cysteine. Arch Dis Child. 1969 Jun;44(235):404–405. doi: 10.1136/adc.44.235.404. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. HALLBERG D. MUCOVISCIDOSIS ILEUS. Acta Chir Scand. 1964 Aug;128:201–209. [PubMed] [Google Scholar]
  7. Hunton D. B., Long W. K., Tsumagari H. Y. Meconium ileus equivalent: an adult complication of fibrocystic disease. Gastroenterology. 1966 Jan;50(1):99–106. [PubMed] [Google Scholar]
  8. Kopel F. B. Gastrointestinal manifestations of cystic fibrosis. Gastroenterology. 1972 Mar;62(3):483–491. [PubMed] [Google Scholar]
  9. Lillibridge C. B., Docter J. M., Eidelman S. Oral administration of n-acetyl cysteine in the prophylaxis of "meconium ileus equivalent". J Pediatr. 1967 Dec;71(6):887–889. doi: 10.1016/s0022-3476(67)80019-2. [DOI] [PubMed] [Google Scholar]
  10. MULLINS F., TALAMO R., DISANTAGNESE P. A. LATE INTESTINAL COMPLICATIONS OF CYSTIC FIBROSIS. JAMA. 1965 May 31;192:741–746. doi: 10.1001/jama.1965.03080220005001. [DOI] [PubMed] [Google Scholar]
  11. SNYDER W. H., Jr, GWINN J. L., LANDING B. H., ASAY L. D. FECAL RETENTION IN CHILDREN WITH CYSTIC FIBROSIS. REPORT OF THREE CASES. Pediatrics. 1964 Jul;34:72–77. [PubMed] [Google Scholar]
  12. THOMAIDIS T. S., AREY J. B. THE INTESTINAL LESIONS IN CYSTIC FIBROSIS OF THE PANCREAS. J Pediatr. 1963 Sep;63:444–453. doi: 10.1016/s0022-3476(63)80434-5. [DOI] [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES