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. 1999 Apr 7;266(1420):649–656. doi: 10.1098/rspb.1999.0685

Hybridizing Old and New World camelids: Camelus dromedarius x Lama guanicoe.

J A Skidmore 1, M Billah 1, M Binns 1, R V Short 1, W R Allen 1
PMCID: PMC1689826  PMID: 10331286

Abstract

Thirty female dromedary camels were inseminated on a total of 50 occasions with 2-4 ml of fresh guanaco semen diluted with an equal volume of commercially available camel semen extender. Similarly, nine female guanacos were inseminated on 34 occasions with 4-6 ml of fresh, diluted camel semen. Only two of the dromedary females conceived; one aborted a female foetus on day 260 of gestation and the other gave birth to a stillborn female calf on day 365. Six conceptions occurred in the female guanacos. Two of these conceptuses, diagnosed by ultrasound, were resorbed between days 25 and 40 of gestation, one female foetus was aborted on day 291, another female foetus was aborted on day 302, and one female calf was stillborn on day 365 of gestation. The sixth foetus, a male, was born prematurely but alive after a 328-day gestation. It had a phenotypic appearance intermediate between that of a camel and a guanaco and its hybrid parentage was confirmed by the DNA fingerprinting of eight llama microsatellites. To our knowledge, this is the first viable hybrid ever to be produced between Old World and New World camelids, which have been reproductively isolated from one another for at least 11 million years. The preponderance of female hybrids is in accordance with Haldane's law. Histological examination of their ovaries revealed a failure of meiosis, with only an occasional abnormal oocyte surrounded by follicle cells. Although the diploid chromosone number of camels and guanacos is the same (2n = 74), sufficient genetic change has taken place to make the pairing of homologous chromosomes no longer possible.

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Selected References

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  1. Allen W. R., Short R. V. Interspecific and extraspecific pregnancies in equids: anything goes. J Hered. 1997 Sep-Oct;88(5):384–392. doi: 10.1093/oxfordjournals.jhered.a023123. [DOI] [PubMed] [Google Scholar]
  2. Arthur G. H., al-Rahim A. T., al-Hindi A. S. Reproduction and genital diseases of the camel. Br Vet J. 1985 Nov-Dec;141(6):650–659. doi: 10.1016/0007-1935(85)90014-4. [DOI] [PubMed] [Google Scholar]
  3. Barker D. J. The Wellcome Foundation Lecture, 1994. The fetal origins of adult disease. Proc Biol Sci. 1995 Oct 23;262(1363):37–43. doi: 10.1098/rspb.1995.0173. [DOI] [PubMed] [Google Scholar]
  4. CHANG M. C., MARSTON J. H., HUNT D. M. RECIPROCAL FERTILIZATION BETWEEN THE DOMESTICATED RABBIT AND THE SNOWSHOE HARE WITH SPECIAL REFERENCE TO INSEMINATION OF RABBITS WITH AN EQUAL NUMBER OF HARE AND RABBIT SPERMATOZOA. J Exp Zool. 1964 Apr;155:437–445. doi: 10.1002/jez.1401550312. [DOI] [PubMed] [Google Scholar]
  5. England B. G., Foote W. C., Cardozo A. G., Matthews D. H., Riera S. Oestrous and mating behaviour in the llama (Llama glama). Anim Behav. 1971 Nov;19(4):722–726. doi: 10.1016/s0003-3472(71)80176-8. [DOI] [PubMed] [Google Scholar]
  6. Hancock J. L., McGovern P. T., Stamp J. T. Failure of gestation of goat x sheep hybrids in goats and sheep. J Reprod Fertil Suppl. 1968 Apr;3(Suppl):29–36. [PubMed] [Google Scholar]
  7. Lang K. D., Wang Y., Plante Y. Fifteen polymorphic dinucleotide microsatellites in llamas and alpacas. Anim Genet. 1996 Aug;27(4):293–293. doi: 10.1111/j.1365-2052.1996.tb00502.x. [DOI] [PubMed] [Google Scholar]
  8. Musa B. E., Abusineina M. E. The oestrous cycle of the camel (Camelus dromedarius). Vet Rec. 1978 Dec 16;103(25):556–557. doi: 10.1136/vr.103.25.556. [DOI] [PubMed] [Google Scholar]
  9. San-Martin M., Copaira M., Zuniga J., Rodreguez R., Bustinza G., Acosta L. Aspects of reproduction in the alpaca. J Reprod Fertil. 1968 Aug;16(3):395–399. doi: 10.1530/jrf.0.0160395. [DOI] [PubMed] [Google Scholar]
  10. Short R. V. An introduction to mammalian interspecific hybrids. J Hered. 1997 Sep-Oct;88(5):355–357. doi: 10.1093/oxfordjournals.jhered.a023117. [DOI] [PubMed] [Google Scholar]
  11. Short R. V. The testis: the witness of the mating system, the site of mutation and the engine of desire. Acta Paediatr Suppl. 1997 Jul;422:3–7. doi: 10.1111/j.1651-2227.1997.tb18336.x. [DOI] [PubMed] [Google Scholar]
  12. Skidmore J. A., Billah M., Allen W. R. The ovarian follicular wave pattern and induction of ovulation in the mated and non-mated one-humped camel (Camelus dromedarius). J Reprod Fertil. 1996 Mar;106(2):185–192. doi: 10.1530/jrf.0.1060185. [DOI] [PubMed] [Google Scholar]
  13. Skidmore J. A., Billah M., Allen W. R. The ovarian follicular wave pattern in the mated and non-mated dromedary camel (Camelus dromedarius). J Reprod Fertil Suppl. 1995;49:545–548. [PubMed] [Google Scholar]
  14. Skidmore J. A., Wooding F. B., Allen W. R. Implantation and early placentation in the one-humped camel (Camelus dromedarius). Placenta. 1996 May;17(4):253–262. doi: 10.1016/s0143-4004(96)90046-6. [DOI] [PubMed] [Google Scholar]
  15. Stanley H. F., Kadwell M., Wheeler J. C. Molecular evolution of the family Camelidae: a mitochondrial DNA study. Proc Biol Sci. 1994 Apr 22;256(1345):1–6. doi: 10.1098/rspb.1994.0041. [DOI] [PubMed] [Google Scholar]
  16. Steven D. H., Burton G. J., Sumar J., Nathanielsz P. W. Ultrastructural observations on the placenta of the alpaca (Lama pacos). Placenta. 1980 Jan-Mar;1(1):21–32. doi: 10.1016/s0143-4004(80)80013-0. [DOI] [PubMed] [Google Scholar]

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