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. 2002 Jun 7;269(1496):1167–1171. doi: 10.1098/rspb.2002.1989

Epistasis and hybrid sterility in Saccharomyces.

Duncan Greig 1, Rhona H Borts 1, Edward J Louis 1, Michael Travisano 1
PMCID: PMC1691007  PMID: 12061961

Abstract

Hybrid sterility is thought to be due to deleterious epistatic interactions between genes from different species. Here we demonstrate that dominant genic incompatibility does not contribute to sterility in hybrids between Saccharomyces cerevisiae and five closely related species. Sterile diploids were made fertile by genome doubling to produce hybrid tetraploids. Based on these and previous results, we conclude that neither genic incompatibility nor classical chromosomal speciation models apply.

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Selected References

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