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Philosophical Transactions of the Royal Society B: Biological Sciences logoLink to Philosophical Transactions of the Royal Society B: Biological Sciences
. 1997 Nov 29;352(1362):1755–1759. doi: 10.1098/rstb.1997.0158

Memory and anxiety disorders.

R J Mcnally 1
PMCID: PMC1692103  PMID: 9415928

Abstract

Experimental psychopathologists have identified varying patterns in memory bias in people with depressive and anxiety disorders. Individuals suffering from depression tend to exhibit explicit memory deficits for positively-valanced material, and sometimes exhibit biases for retrieving negative self-relevant information as well. Most studies, however, provide scant evidence for implicit memory biases in depression. In contrast to depression, anxiety disorders are rarely associated with enhanced explicit memory for threat-related information (with the exception of panic disorder). Evidence for implicit memory biases for threat in these syndromes is mixed. After providing an overview of findings on memory abnormalities in depressive and anxiety disorders, data from several new studies bearing on posttraumatic stress disorder (PTSD) in Vietnam combat veterans and in women with histories of childhood sexual abuse are presented. Involving directed forgetting, implicit memory and autobiographical cueing paradigms, these experiments point to a pattern of abnormalities linked to PTSD rather than to trauma per se.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amir N., McNally R. J., Riemann B. C., Clements C. Implicit memory bias for threat in panic disorder: application of the 'white noise' paradigm. Behav Res Ther. 1996 Feb;34(2):157–162. doi: 10.1016/0005-7967(95)00054-2. [DOI] [PubMed] [Google Scholar]
  2. Becker E., Rinck M., Margraf J. Memory bias in panic disorder. J Abnorm Psychol. 1994 May;103(2):396–399. doi: 10.1037//0021-843x.103.2.396. [DOI] [PubMed] [Google Scholar]
  3. Brown H. D., Kosslyn S. M., Breiter H. C., Baer L., Jenike M. A. Can patients with obsessive-compulsive disorder discriminate between percepts and mental images? A signal detection analysis. J Abnorm Psychol. 1994 Aug;103(3):445–454. [PubMed] [Google Scholar]
  4. Constans J. I., Foa E. B., Franklin M. E., Mathews A. Memory for actual and imagined events in OC checkers. Behav Res Ther. 1995 Jul;33(6):665–671. doi: 10.1016/0005-7967(94)00095-2. [DOI] [PubMed] [Google Scholar]
  5. Evans J., Williams J. M., O'Loughlin S., Howells K. Autobiographical memory and problem-solving strategies of parasuicide patients. Psychol Med. 1992 May;22(2):399–405. doi: 10.1017/s0033291700030348. [DOI] [PubMed] [Google Scholar]
  6. Jacoby L. L., Dallas M. On the relationship between autobiographical memory and perceptual learning. J Exp Psychol Gen. 1981 Sep;110(3):306–340. doi: 10.1037//0096-3445.110.3.306. [DOI] [PubMed] [Google Scholar]
  7. Kuyken W., Brewin C. R. Autobiographical memory functioning in depression and reports of early abuse. J Abnorm Psychol. 1995 Nov;104(4):585–591. doi: 10.1037//0021-843x.104.4.585. [DOI] [PubMed] [Google Scholar]
  8. MacLeod C., McLaughlin K. Implicit and explicit memory bias in anxiety: a conceptual replication. Behav Res Ther. 1995 Jan;33(1):1–14. doi: 10.1016/0005-7967(94)e0004-3. [DOI] [PubMed] [Google Scholar]
  9. Mathews A., MacLeod C. Cognitive approaches to emotion and emotional disorders. Annu Rev Psychol. 1994;45:25–50. doi: 10.1146/annurev.ps.45.020194.000325. [DOI] [PubMed] [Google Scholar]
  10. Mathews A., Mogg K., Kentish J., Eysenck M. Effect of psychological treatment on cognitive bias in generalized anxiety disorder. Behav Res Ther. 1995 Mar;33(3):293–303. doi: 10.1016/0005-7967(94)e0022-b. [DOI] [PubMed] [Google Scholar]
  11. Mathews A., Mogg K., May J., Eysenck M. Implicit and explicit memory bias in anxiety. J Abnorm Psychol. 1989 Aug;98(3):236–240. doi: 10.1037//0021-843x.98.3.236. [DOI] [PubMed] [Google Scholar]
  12. McNally R. J. Cognitive bias in the anxiety disorders. Nebr Symp Motiv. 1996;43:211–250. [PubMed] [Google Scholar]
  13. McNally R. J., Kohlbeck P. A. Reality monitoring in obsessive-compulsive disorder. Behav Res Ther. 1993 Mar;31(3):249–253. doi: 10.1016/0005-7967(93)90023-n. [DOI] [PubMed] [Google Scholar]
  14. McNally R. J., Lasko N. B., Macklin M. L., Pitman R. K. Autobiographical memory disturbance in combat-related posttraumatic stress disorder. Behav Res Ther. 1995 Jul;33(6):619–630. doi: 10.1016/0005-7967(95)00007-k. [DOI] [PubMed] [Google Scholar]
  15. Mogg K., Mathews A. Is there a self-referent mood-congruent recall bias in anxiety? Behav Res Ther. 1990;28(1):91–92. doi: 10.1016/0005-7967(90)90060-v. [DOI] [PubMed] [Google Scholar]
  16. Mogg K., Mathews A., Weinman J. Memory bias in clinical anxiety. J Abnorm Psychol. 1987 May;96(2):94–98. doi: 10.1037//0021-843x.96.2.94. [DOI] [PubMed] [Google Scholar]
  17. Otto M. W., McNally R. J., Pollack M. H., Chen E., Rosenbaum J. F. Hemispheric laterality and memory bias for threat in anxiety disorders. J Abnorm Psychol. 1994 Nov;103(4):828–831. doi: 10.1037/0021-843X.103.4.828. [DOI] [PubMed] [Google Scholar]
  18. Rapee R. M., McCallum S. L., Melville L. F., Ravenscroft H., Rodney J. M. Memory bias in social phobia. Behav Res Ther. 1994 Jan;32(1):89–99. doi: 10.1016/0005-7967(94)90087-6. [DOI] [PubMed] [Google Scholar]
  19. Roediger H. L., 3rd Implicit memory. Retention without remembering. Am Psychol. 1990 Sep;45(9):1043–1056. doi: 10.1037//0003-066x.45.9.1043. [DOI] [PubMed] [Google Scholar]
  20. Schacter D. L. Understanding implicit memory. A cognitive neuroscience approach. Am Psychol. 1992 Apr;47(4):559–569. doi: 10.1037//0003-066x.47.4.559. [DOI] [PubMed] [Google Scholar]
  21. Terr L. C. Childhood traumas: an outline and overview. Am J Psychiatry. 1991 Jan;148(1):10–20. doi: 10.1176/ajp.148.1.10. [DOI] [PubMed] [Google Scholar]
  22. Watts F. N., Coyle K. Phobics show poor recall of anxiety words. Br J Med Psychol. 1993 Dec;66(Pt 4):373–382. doi: 10.1111/j.2044-8341.1993.tb01763.x. [DOI] [PubMed] [Google Scholar]
  23. Wilhelm S., McNally R. J., Baer L., Florin I. Autobiographical memory in obsessive-compulsive disorder. Br J Clin Psychol. 1997 Feb;36(Pt 1):21–31. doi: 10.1111/j.2044-8260.1997.tb01227.x. [DOI] [PubMed] [Google Scholar]

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