Abstract
Functional anatomical studies indicate that a set of neural signals in parietal and frontal cortex mediates the covert allocation of attention to visual locations across a wide variety of visual tasks. This frontoparietal network includes areas, such as the frontal eye field and supplementary eye field. This anatomical overlap suggests that shifts of attention to visual locations of objects recruit areas involved in oculomotor programming and execution. Finally, the fronto-parietal network may be the source of spatial attentional modulations in the ventral visual system during object recognition or discrimination.
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- Andersen R. A., Bracewell R. M., Barash S., Gnadt J. W., Fogassi L. Eye position effects on visual, memory, and saccade-related activity in areas LIP and 7a of macaque. J Neurosci. 1990 Apr;10(4):1176–1196. doi: 10.1523/JNEUROSCI.10-04-01176.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Andersen R. A. Encoding of intention and spatial location in the posterior parietal cortex. Cereb Cortex. 1995 Sep-Oct;5(5):457–469. doi: 10.1093/cercor/5.5.457. [DOI] [PubMed] [Google Scholar]
- Anderson T. J., Jenkins I. H., Brooks D. J., Hawken M. B., Frackowiak R. S., Kennard C. Cortical control of saccades and fixation in man. A PET study. Brain. 1994 Oct;117(Pt 5):1073–1084. doi: 10.1093/brain/117.5.1073. [DOI] [PubMed] [Google Scholar]
- Ashbridge E., Walsh V., Cowey A. Temporal aspects of visual search studied by transcranial magnetic stimulation. Neuropsychologia. 1997 Aug;35(8):1121–1131. doi: 10.1016/s0028-3932(97)00003-1. [DOI] [PubMed] [Google Scholar]
- Astruc J. Corticofugal connections of area 8 (frontal eye field) in Macaca mulatta. Brain Res. 1971 Oct 29;33(2):241–256. doi: 10.1016/0006-8993(71)90100-4. [DOI] [PubMed] [Google Scholar]
- Bodis-Wollner I., Bucher S. F., Seelos K. C., Paulus W., Reiser M., Oertel W. H. Functional MRI mapping of occipital and frontal cortical activity during voluntary and imagined saccades. Neurology. 1997 Aug;49(2):416–420. doi: 10.1212/wnl.49.2.416. [DOI] [PubMed] [Google Scholar]
- Bruce C. J., Goldberg M. E. Primate frontal eye fields. I. Single neurons discharging before saccades. J Neurophysiol. 1985 Mar;53(3):603–635. doi: 10.1152/jn.1985.53.3.603. [DOI] [PubMed] [Google Scholar]
- Bushnell M. C., Goldberg M. E., Robinson D. L. Behavioral enhancement of visual responses in monkey cerebral cortex. I. Modulation in posterior parietal cortex related to selective visual attention. J Neurophysiol. 1981 Oct;46(4):755–772. doi: 10.1152/jn.1981.46.4.755. [DOI] [PubMed] [Google Scholar]
- Chelazzi L., Biscaldi M., Corbetta M., Peru A., Tassinari G., Berlucchi G. Oculomotor activity and visual spatial attention. Behav Brain Res. 1995 Nov;71(1-2):81–88. doi: 10.1016/0166-4328(95)00134-4. [DOI] [PubMed] [Google Scholar]
- Colby C. L., Duhamel J. R., Goldberg M. E. Oculocentric spatial representation in parietal cortex. Cereb Cortex. 1995 Sep-Oct;5(5):470–481. doi: 10.1093/cercor/5.5.470. [DOI] [PubMed] [Google Scholar]
- Colby C. L., Duhamel J. R., Goldberg M. E. Visual, presaccadic, and cognitive activation of single neurons in monkey lateral intraparietal area. J Neurophysiol. 1996 Nov;76(5):2841–2852. doi: 10.1152/jn.1996.76.5.2841. [DOI] [PubMed] [Google Scholar]
- Corbetta M. Frontoparietal cortical networks for directing attention and the eye to visual locations: identical, independent, or overlapping neural systems? Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):831–838. doi: 10.1073/pnas.95.3.831. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Corbetta M., Miezin F. M., Shulman G. L., Petersen S. E. A PET study of visuospatial attention. J Neurosci. 1993 Mar;13(3):1202–1226. doi: 10.1523/JNEUROSCI.13-03-01202.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Corbetta M., Shulman G. L., Miezin F. M., Petersen S. E. Superior parietal cortex activation during spatial attention shifts and visual feature conjunction. Science. 1995 Nov 3;270(5237):802–805. doi: 10.1126/science.270.5237.802. [DOI] [PubMed] [Google Scholar]
- Darby D. G., Nobre A. C., Thangaraj V., Edelman R., Mesulam M. M., Warach S. Cortical activation in the human brain during lateral saccades using EPISTAR functional magnetic resonance imaging. Neuroimage. 1996 Feb;3(1):53–62. doi: 10.1006/nimg.1996.0006. [DOI] [PubMed] [Google Scholar]
- Desimone R., Duncan J. Neural mechanisms of selective visual attention. Annu Rev Neurosci. 1995;18:193–222. doi: 10.1146/annurev.ne.18.030195.001205. [DOI] [PubMed] [Google Scholar]
- Downing C. J. Expectancy and visual-spatial attention: effects on perceptual quality. J Exp Psychol Hum Percept Perform. 1988 May;14(2):188–202. doi: 10.1037//0096-1523.14.2.188. [DOI] [PubMed] [Google Scholar]
- Drury H. A., Van Essen D. C., Anderson C. H., Lee C. W., Coogan T. A., Lewis J. W. Computerized mappings of the cerebral cortex: a multiresolution flattening method and a surface-based coordinate system. J Cogn Neurosci. 1996;8(1):1–28. doi: 10.1162/jocn.1996.8.1.1. [DOI] [PubMed] [Google Scholar]
- Duncan J., Humphreys G. W. Visual search and stimulus similarity. Psychol Rev. 1989 Jul;96(3):433–458. doi: 10.1037/0033-295x.96.3.433. [DOI] [PubMed] [Google Scholar]
- Fox P. T., Fox J. M., Raichle M. E., Burde R. M. The role of cerebral cortex in the generation of voluntary saccades: a positron emission tomographic study. J Neurophysiol. 1985 Aug;54(2):348–369. doi: 10.1152/jn.1985.54.2.348. [DOI] [PubMed] [Google Scholar]
- Friedman-Hill S. R., Robertson L. C., Treisman A. Parietal contributions to visual feature binding: evidence from a patient with bilateral lesions. Science. 1995 Aug 11;269(5225):853–855. doi: 10.1126/science.7638604. [DOI] [PubMed] [Google Scholar]
- Hawkins H. L., Hillyard S. A., Luck S. J., Mouloua M., Downing C. J., Woodward D. P. Visual attention modulates signal detectability. J Exp Psychol Hum Percept Perform. 1990 Nov;16(4):802–811. doi: 10.1037//0096-1523.16.4.802. [DOI] [PubMed] [Google Scholar]
- Heinze H. J., Mangun G. R., Burchert W., Hinrichs H., Scholz M., Münte T. F., Gös A., Scherg M., Johannes S., Hundeshagen H. Combined spatial and temporal imaging of brain activity during visual selective attention in humans. Nature. 1994 Dec 8;372(6506):543–546. doi: 10.1038/372543a0. [DOI] [PubMed] [Google Scholar]
- Henderson J. M. Spatial precues affect target discrimination in the absence of visual noise. J Exp Psychol Hum Percept Perform. 1996 Jun;22(3):780–787. doi: 10.1037//0096-1523.22.3.780. [DOI] [PubMed] [Google Scholar]
- Hoffman J. E., Subramaniam B. The role of visual attention in saccadic eye movements. Percept Psychophys. 1995 Aug;57(6):787–795. doi: 10.3758/bf03206794. [DOI] [PubMed] [Google Scholar]
- Klein R. M. Perceptual-motor expectancies interact with covert visual orienting under conditions of endogenous but not exogenous control. Can J Exp Psychol. 1994 Jun;48(2):167–181. doi: 10.1037/1196-1961.48.2.167. [DOI] [PubMed] [Google Scholar]
- Kustov A. A., Robinson D. L. Shared neural control of attentional shifts and eye movements. Nature. 1996 Nov 7;384(6604):74–77. doi: 10.1038/384074a0. [DOI] [PubMed] [Google Scholar]
- Lang W., Petit L., Höllinger P., Pietrzyk U., Tzourio N., Mazoyer B., Berthoz A. A positron emission tomography study of oculomotor imagery. Neuroreport. 1994 Apr 14;5(8):921–924. doi: 10.1097/00001756-199404000-00017. [DOI] [PubMed] [Google Scholar]
- Law I., Svarer C., Holm S., Paulson O. B. The activation pattern in normal humans during suppression, imagination and performance of saccadic eye movements. Acta Physiol Scand. 1997 Nov;161(3):419–434. doi: 10.1046/j.1365-201X.1997.00207.x. [DOI] [PubMed] [Google Scholar]
- Leichnetz G. R., Spencer R. F., Smith D. J. Cortical projections to nuclei adjacent to the oculomotor complex in the medial dien-mesencephalic tegmentum in the monkey. J Comp Neurol. 1984 Sep 20;228(3):359–387. doi: 10.1002/cne.902280306. [DOI] [PubMed] [Google Scholar]
- Luck S. J., Chelazzi L., Hillyard S. A., Desimone R. Neural mechanisms of spatial selective attention in areas V1, V2, and V4 of macaque visual cortex. J Neurophysiol. 1997 Jan;77(1):24–42. doi: 10.1152/jn.1997.77.1.24. [DOI] [PubMed] [Google Scholar]
- Luck S. J., Hillyard S. A., Mouloua M., Hawkins H. L. Mechanisms of visual-spatial attention: resource allocation or uncertainty reduction? J Exp Psychol Hum Percept Perform. 1996 Jun;22(3):725–737. doi: 10.1037//0096-1523.22.3.725. [DOI] [PubMed] [Google Scholar]
- Luna B., Thulborn K. R., Strojwas M. H., McCurtain B. J., Berman R. A., Genovese C. R., Sweeney J. A. Dorsal cortical regions subserving visually guided saccades in humans: an fMRI study. Cereb Cortex. 1998 Jan-Feb;8(1):40–47. doi: 10.1093/cercor/8.1.40. [DOI] [PubMed] [Google Scholar]
- Mesulam M. M. Large-scale neurocognitive networks and distributed processing for attention, language, and memory. Ann Neurol. 1990 Nov;28(5):597–613. doi: 10.1002/ana.410280502. [DOI] [PubMed] [Google Scholar]
- Müri R. M., Iba-Zizen M. T., Derosier C., Cabanis E. A., Pierrot-Deseilligny C. Location of the human posterior eye field with functional magnetic resonance imaging. J Neurol Neurosurg Psychiatry. 1996 Apr;60(4):445–448. doi: 10.1136/jnnp.60.4.445. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nobre A. C., Sebestyen G. N., Gitelman D. R., Mesulam M. M., Frackowiak R. S., Frith C. D. Functional localization of the system for visuospatial attention using positron emission tomography. Brain. 1997 Mar;120(Pt 3):515–533. doi: 10.1093/brain/120.3.515. [DOI] [PubMed] [Google Scholar]
- O'Driscoll G. A., Alpert N. M., Matthysse S. W., Levy D. L., Rauch S. L., Holzman P. S. Functional neuroanatomy of antisaccade eye movements investigated with positron emission tomography. Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):925–929. doi: 10.1073/pnas.92.3.925. [DOI] [PMC free article] [PubMed] [Google Scholar]
- O'Sullivan E. P., Jenkins I. H., Henderson L., Kennard C., Brooks D. J. The functional anatomy of remembered saccades: a PET study. Neuroreport. 1995 Nov 13;6(16):2141–2144. doi: 10.1097/00001756-199511000-00011. [DOI] [PubMed] [Google Scholar]
- Paus T. Location and function of the human frontal eye-field: a selective review. Neuropsychologia. 1996 Jun;34(6):475–483. doi: 10.1016/0028-3932(95)00134-4. [DOI] [PubMed] [Google Scholar]
- Paus T., Marrett S., Worsley K. J., Evans A. C. Extraretinal modulation of cerebral blood flow in the human visual cortex: implications for saccadic suppression. J Neurophysiol. 1995 Nov;74(5):2179–2183. doi: 10.1152/jn.1995.74.5.2179. [DOI] [PubMed] [Google Scholar]
- Paus T., Petrides M., Evans A. C., Meyer E. Role of the human anterior cingulate cortex in the control of oculomotor, manual, and speech responses: a positron emission tomography study. J Neurophysiol. 1993 Aug;70(2):453–469. doi: 10.1152/jn.1993.70.2.453. [DOI] [PubMed] [Google Scholar]
- Petit L., Clark V. P., Ingeholm J., Haxby J. V. Dissociation of saccade-related and pursuit-related activation in human frontal eye fields as revealed by fMRI. J Neurophysiol. 1997 Jun;77(6):3386–3390. doi: 10.1152/jn.1997.77.6.3386. [DOI] [PubMed] [Google Scholar]
- Petit L., Orssaud C., Tzourio N., Crivello F., Berthoz A., Mazoyer B. Functional anatomy of a prelearned sequence of horizontal saccades in humans. J Neurosci. 1996 Jun 1;16(11):3714–3726. doi: 10.1523/JNEUROSCI.16-11-03714.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Petit L., Orssaud C., Tzourio N., Salamon G., Mazoyer B., Berthoz A. PET study of voluntary saccadic eye movements in humans: basal ganglia-thalamocortical system and cingulate cortex involvement. J Neurophysiol. 1993 Apr;69(4):1009–1017. doi: 10.1152/jn.1993.69.4.1009. [DOI] [PubMed] [Google Scholar]
- Posner M. I., Snyder C. R., Davidson B. J. Attention and the detection of signals. J Exp Psychol. 1980 Jun;109(2):160–174. [PubMed] [Google Scholar]
- Prinzmetal W., Presti D. E., Posner M. I. Does attention affect visual feature integration? J Exp Psychol Hum Percept Perform. 1986 Aug;12(3):361–369. doi: 10.1037//0096-1523.12.3.361. [DOI] [PubMed] [Google Scholar]
- Rafal R. D., Calabresi P. A., Brennan C. W., Sciolto T. K. Saccade preparation inhibits reorienting to recently attended locations. J Exp Psychol Hum Percept Perform. 1989 Nov;15(4):673–685. doi: 10.1037//0096-1523.15.4.673. [DOI] [PubMed] [Google Scholar]
- Remington R. W. Attention and saccadic eye movements. J Exp Psychol Hum Percept Perform. 1980 Nov;6(4):726–744. doi: 10.1037//0096-1523.6.4.726. [DOI] [PubMed] [Google Scholar]
- Rizzolatti G., Riggio L., Dascola I., Umiltá C. Reorienting attention across the horizontal and vertical meridians: evidence in favor of a premotor theory of attention. Neuropsychologia. 1987;25(1A):31–40. doi: 10.1016/0028-3932(87)90041-8. [DOI] [PubMed] [Google Scholar]
- Robinson D. A., Fuchs A. F. Eye movements evoked by stimulation of frontal eye fields. J Neurophysiol. 1969 Sep;32(5):637–648. doi: 10.1152/jn.1969.32.5.637. [DOI] [PubMed] [Google Scholar]
- Robinson D. L., Bowman E. M., Kertzman C. Covert orienting of attention in macaques. II. Contributions of parietal cortex. J Neurophysiol. 1995 Aug;74(2):698–712. doi: 10.1152/jn.1995.74.2.698. [DOI] [PubMed] [Google Scholar]
- Schall J. D., Hanes D. P. Neural basis of saccade target selection in frontal eye field during visual search. Nature. 1993 Dec 2;366(6454):467–469. doi: 10.1038/366467a0. [DOI] [PubMed] [Google Scholar]
- Schlag J., Schlag-Rey M., Pigarev I. Supplementary eye field: influence of eye position on neural signals of fixation. Exp Brain Res. 1992;90(2):302–306. doi: 10.1007/BF00227242. [DOI] [PubMed] [Google Scholar]
- Shepherd M., Findlay J. M., Hockey R. J. The relationship between eye movements and spatial attention. Q J Exp Psychol A. 1986 Aug;38(3):475–491. doi: 10.1080/14640748608401609. [DOI] [PubMed] [Google Scholar]
- Shook B. L., Schlag-Rey M., Schlag J. Primate supplementary eye field. II. Comparative aspects of connections with the thalamus, corpus striatum, and related forebrain nuclei. J Comp Neurol. 1991 May 22;307(4):562–583. doi: 10.1002/cne.903070405. [DOI] [PubMed] [Google Scholar]
- Steinmetz M. A., Constantinidis C. Neurophysiological evidence for a role of posterior parietal cortex in redirecting visual attention. Cereb Cortex. 1995 Sep-Oct;5(5):448–456. doi: 10.1093/cercor/5.5.448. [DOI] [PubMed] [Google Scholar]
- Sweeney J. A., Mintun M. A., Kwee S., Wiseman M. B., Brown D. L., Rosenberg D. R., Carl J. R. Positron emission tomography study of voluntary saccadic eye movements and spatial working memory. J Neurophysiol. 1996 Jan;75(1):454–468. doi: 10.1152/jn.1996.75.1.454. [DOI] [PubMed] [Google Scholar]
- Thompson K. G., Bichot N. P., Schall J. D. Dissociation of visual discrimination from saccade programming in macaque frontal eye field. J Neurophysiol. 1997 Feb;77(2):1046–1050. doi: 10.1152/jn.1997.77.2.1046. [DOI] [PubMed] [Google Scholar]
- Treisman A. M., Gelade G. A feature-integration theory of attention. Cogn Psychol. 1980 Jan;12(1):97–136. doi: 10.1016/0010-0285(80)90005-5. [DOI] [PubMed] [Google Scholar]
- Treisman A., Gormican S. Feature analysis in early vision: evidence from search asymmetries. Psychol Rev. 1988 Jan;95(1):15–48. doi: 10.1037/0033-295x.95.1.15. [DOI] [PubMed] [Google Scholar]
- Treisman A. Search, similarity, and integration of features between and within dimensions. J Exp Psychol Hum Percept Perform. 1991 Aug;17(3):652–676. doi: 10.1037//0096-1523.17.3.652. [DOI] [PubMed] [Google Scholar]
- Ullman S. Visual routines. Cognition. 1984 Dec;18(1-3):97–159. doi: 10.1016/0010-0277(84)90023-4. [DOI] [PubMed] [Google Scholar]
- Van Essen D. C., Drury H. A. Structural and functional analyses of human cerebral cortex using a surface-based atlas. J Neurosci. 1997 Sep 15;17(18):7079–7102. doi: 10.1523/JNEUROSCI.17-18-07079.1997. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Vandenberghe R., Duncan J., Dupont P., Ward R., Poline J. B., Bormans G., Michiels J., Mortelmans L., Orban G. A. Attention to one or two features in left or right visual field: a positron emission tomography study. J Neurosci. 1997 May 15;17(10):3739–3750. doi: 10.1523/JNEUROSCI.17-10-03739.1997. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Vandenberghe R., Dupont P., De Bruyn B., Bormans G., Michiels J., Mortelmans L., Orban G. A. The influence of stimulus location on the brain activation pattern in detection and orientation discrimination. A PET study of visual attention. Brain. 1996 Aug;119(Pt 4):1263–1276. doi: 10.1093/brain/119.4.1263. [DOI] [PubMed] [Google Scholar]
- Wolfe J. M., Cave K. R., Franzel S. L. Guided search: an alternative to the feature integration model for visual search. J Exp Psychol Hum Percept Perform. 1989 Aug;15(3):419–433. doi: 10.1037//0096-1523.15.3.419. [DOI] [PubMed] [Google Scholar]
- Yantis S., Jonides J. Abrupt visual onsets and selective attention: voluntary versus automatic allocation. J Exp Psychol Hum Percept Perform. 1990 Feb;16(1):121–134. doi: 10.1037//0096-1523.16.1.121. [DOI] [PubMed] [Google Scholar]