Skip to main content
Philosophical Transactions of the Royal Society B: Biological Sciences logoLink to Philosophical Transactions of the Royal Society B: Biological Sciences
. 1999 Dec 29;354(1392):1923–1939. doi: 10.1098/rstb.1999.0532

Life: past, present and future.

K H Nealson 1, P G Conrad 1
PMCID: PMC1692713  PMID: 10670014

Abstract

Molecular methods of taxonomy and phylogeny have changed the way in which life on earth is viewed; they have allowed us to transition from a eukaryote-centric (five-kingdoms) view of the planet to one that is peculiarly prokarote-centric, containing three kingdoms, two of which are prokaryotic unicells. These prokaryotes are distinguished from their eukaryotic counterparts by their toughness, tenacity and metabolic diversity. Realization of these features has, in many ways, changed the way we feel about life on earth, about the nature of life past and about the possibility of finding life elsewhere. In essence, the limits of life on this planet have expanded to such a degree that our thoughts of both past and future life have been altered. The abilities of prokaryotes to withstand many extreme conditions has led to the term extremophiles, used to describe the organisms that thrive under conditions thought just a few years ago, to be inconsistent with life. Perhaps the most extensive adaptation to extreme conditions, however, is represented by the ability of many bacteria to survive nutrient conditions not compatible with eukaryotic life. Prokaryotes have evolved to use nearly every redox couple that is in abundance on earth, filling the metabolic niches left behind by the oxygen-using, carbon-eating eukaryotes. This metabolic plasticity leads to a common feature in physically stratified environments of layered microbial communities, chemical indicators of the metabolic diversity of the prokaryotes. Such 'metabolic extremophily' forms a backdrop by which we can view the energy flow of life on this planet, think about what the evolutionary past of the planet might have been, and plan ways to look for life elsewhere, using the knowledge of energy flow on earth.

Full Text

The Full Text of this article is available as a PDF (889.6 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Canfield D. E., Teske A. Late Proterozoic rise in atmospheric oxygen concentration inferred from phylogenetic and sulphur-isotope studies. Nature. 1996 Jul 11;382(6587):127–132. doi: 10.1038/382127a0. [DOI] [PubMed] [Google Scholar]
  2. Des Marais D. J., Strauss H., Summons R. E., Hayes J. M. Carbon isotope evidence for the stepwise oxidation of the Proterozoic environment. Nature. 1992 Oct 15;359(6396):605–609. doi: 10.1038/359605a0. [DOI] [PubMed] [Google Scholar]
  3. Ehrenreich A., Widdel F. Anaerobic oxidation of ferrous iron by purple bacteria, a new type of phototrophic metabolism. Appl Environ Microbiol. 1994 Dec;60(12):4517–4526. doi: 10.1128/aem.60.12.4517-4526.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Friedmann E. I. Endolithic microorganisms in the antarctic cold desert. Science. 1982 Feb 26;215(4536):1045–1053. doi: 10.1126/science.215.4536.1045. [DOI] [PubMed] [Google Scholar]
  5. Holland H. D., Rye R. Evidence in pre-2.2 Ga paleosols for the early evolution of atmospheric oxygen and terrestrial biota: comment and reply. Geology. 1997 Sep;25(9):857–858. doi: 10.1130/0091-7613(1997)025<0857:eipgpf>2.3.co;2. [DOI] [PubMed] [Google Scholar]
  6. Jørgensen B. B., Revsbech N. P., Blackburn T. H., Cohen Y. Diurnal cycle of oxygen and sulfide microgradients and microbial photosynthesis in a cyanobacterial mat sediment. Appl Environ Microbiol. 1979 Jul;38(1):46–58. doi: 10.1128/aem.38.1.46-58.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Knoll A. H. The early evolution of eukaryotes: a geological perspective. Science. 1992 May 1;256(5057):622–627. doi: 10.1126/science.1585174. [DOI] [PubMed] [Google Scholar]
  8. MacGregor B. J., Moser D. P., Alm E. W., Nealson K. H., Stahl D. A. Crenarchaeota in Lake Michigan sediment. Appl Environ Microbiol. 1997 Mar;63(3):1178–1181. doi: 10.1128/aem.63.3.1178-1181.1997. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mojzsis S. J., Arrhenius G., McKeegan K. D., Harrison T. M., Nutman A. P., Friend C. R. Evidence for life on Earth before 3,800 million years ago. Nature. 1996 Nov 7;384(6604):55–59. doi: 10.1038/384055a0. [DOI] [PubMed] [Google Scholar]
  10. Nealson K. H. Post-Viking microbiology: new approaches, new data, new insights. Orig Life Evol Biosph. 1999 Jan;29(1):73–93. doi: 10.1023/a:1006515817767. [DOI] [PubMed] [Google Scholar]
  11. Nealson K. H., Saffarini D. Iron and manganese in anaerobic respiration: environmental significance, physiology, and regulation. Annu Rev Microbiol. 1994;48:311–343. doi: 10.1146/annurev.mi.48.100194.001523. [DOI] [PubMed] [Google Scholar]
  12. Nealson K. H. Sediment bacteria: who's there, what are they doing, and what's new? Annu Rev Earth Planet Sci. 1997;25:403–434. doi: 10.1146/annurev.earth.25.1.403. [DOI] [PubMed] [Google Scholar]
  13. Nealson K. H. The limits of life on Earth and searching for life on Mars. J Geophys Res. 1997 Oct 25;102(E10):23,675-86. [PubMed] [Google Scholar]
  14. Olsen G. J., Woese C. R., Overbeek R. The winds of (evolutionary) change: breathing new life into microbiology. J Bacteriol. 1994 Jan;176(1):1–6. doi: 10.1128/jb.176.1.1-6.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Rye R., Holland H. D. Paleosols and the evolution of atmospheric oxygen: a critical review. Am J Sci. 1998 Oct;298(8):621–672. doi: 10.2475/ajs.298.8.621. [DOI] [PubMed] [Google Scholar]
  16. Shi T., Reeves R. H., Gilichinsky D. A., Friedmann E. I. Characterization of viable bacteria from Siberian permafrost by 16S rDNA sequencing. Microb Ecol. 1997 May-Jun;33(3):169–179. doi: 10.1007/s002489900019. [DOI] [PubMed] [Google Scholar]
  17. Woese C. R. Bacterial evolution. Microbiol Rev. 1987 Jun;51(2):221–271. doi: 10.1128/mr.51.2.221-271.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Woese C. R. There must be a prokaryote somewhere: microbiology's search for itself. Microbiol Rev. 1994 Mar;58(1):1–9. doi: 10.1128/mr.58.1.1-9.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Philosophical Transactions of the Royal Society B: Biological Sciences are provided here courtesy of The Royal Society

RESOURCES