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American Journal of Public Health logoLink to American Journal of Public Health
. 1992 May;82(5):675–679. doi: 10.2105/ajph.82.5.675

Pregnancy-induced hypertension in North Carolina, 1988 and 1989.

D A Savitz 1, J Zhang 1
PMCID: PMC1694130  PMID: 1566945

Abstract

INTRODUCTION. Pregnancy-induced hypertension (PIH) is a highly prevalent pregnancy complication with adverse effects on maternal and infant health. Epidemiologic research concerning its etiology is limited. METHODS. Birth records from North Carolina for the period 1988 through 1989 included an indication of the presence of PIH. The risk of PIH was examined in relation to several maternal characteristics and exposures, including reproductive history, demographic characteristics, and tobacco use during pregnancy. Risk ratio estimates, adjusted for confounders, were calculated contrasting PIH among exposed vs unexposed women. RESULTS. The overall risk of PIH was 43.1 per 1000 births, with multiple pregnancies, nulliparity, and advanced maternal age associated with markedly increased risks. Tobacco use was inversely associated with PIH, and Blacks and Whites were at virtually equal risk. CONCLUSIONS. Problems in diagnosis and classification impede research in this area, with birth certificates limited in quality and breadth of information. Nonetheless, several patterns emerged that are worthy of further epidemiologic evaluation using more sophisticated designs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Belizán J. M., Villar J., Repke J. The relationship between calcium intake and pregnancy-induced hypertension: up-to-date evidence. Am J Obstet Gynecol. 1988 Apr;158(4):898–902. doi: 10.1016/0002-9378(88)90091-9. [DOI] [PubMed] [Google Scholar]
  2. Campbell D. M., MacGillivray I., Carr-Hill R. Pre-eclampsia in second pregnancy. Br J Obstet Gynaecol. 1985 Feb;92(2):131–140. doi: 10.1111/j.1471-0528.1985.tb01064.x. [DOI] [PubMed] [Google Scholar]
  3. Chesley L. C. History and epidemiology of preeclampsia-eclampsia. Clin Obstet Gynecol. 1984 Dec;27(4):801–820. doi: 10.1097/00003081-198412000-00004. [DOI] [PubMed] [Google Scholar]
  4. Davey D. A., MacGillivray I. The classification and definition of the hypertensive disorders of pregnancy. Am J Obstet Gynecol. 1988 Apr;158(4):892–898. doi: 10.1016/0002-9378(88)90090-7. [DOI] [PubMed] [Google Scholar]
  5. Duffus G. M., MacGillivray I. The incidence of pre-eclamptic toxaemia in smokers and non-smokers. Lancet. 1968 May 11;1(7550):994–995. doi: 10.1016/s0140-6736(68)91106-9. [DOI] [PubMed] [Google Scholar]
  6. Eskenazi B., Bracken M. B., Holford T. R., Grady J. Exposure to organic solvents and hypertensive disorders of pregnancy. Am J Ind Med. 1988;14(2):177–188. doi: 10.1002/ajim.4700140208. [DOI] [PubMed] [Google Scholar]
  7. Frost F., Starzyk P., George S., McLaughlin J. F. Birth complication reporting: the effect of birth certificate design. Am J Public Health. 1984 May;74(5):505–506. doi: 10.2105/ajph.74.5.505. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lindheimer M. D., Katz A. I. Hypertension in pregnancy. N Engl J Med. 1985 Sep 12;313(11):675–680. doi: 10.1056/NEJM198509123131107. [DOI] [PubMed] [Google Scholar]
  9. Lindmark G., Lindberg B., Högstedt S. The incidence of hypertensive disease in pregnancy. Acta Obstet Gynecol Scand Suppl. 1984;118:29–32. doi: 10.3109/00016348409157119. [DOI] [PubMed] [Google Scholar]
  10. Marcoux S., Brisson J., Fabia J. The effect of cigarette smoking on the risk of preeclampsia and gestational hypertension. Am J Epidemiol. 1989 Nov;130(5):950–957. doi: 10.1093/oxfordjournals.aje.a115427. [DOI] [PubMed] [Google Scholar]
  11. Marcoux S., Brisson J., Fabia J. The effect of leisure time physical activity on the risk of pre-eclampsia and gestational hypertension. J Epidemiol Community Health. 1989 Jun;43(2):147–152. doi: 10.1136/jech.43.2.147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Prager K., Malin H., Spiegler D., Van Natta P., Placek P. J. Smoking and drinking behavior before and during pregnancy of married mothers of live-born infants and stillborn infants. Public Health Rep. 1984 Mar-Apr;99(2):117–127. [PMC free article] [PubMed] [Google Scholar]
  13. Rabinowitz M., Bellinger D., Leviton A., Needleman H., Schoenbaum S. Pregnancy hypertension, blood pressure during labor, and blood lead levels. Hypertension. 1987 Oct;10(4):447–451. doi: 10.1161/01.hyp.10.4.447. [DOI] [PubMed] [Google Scholar]
  14. Saftlas A. F., Olson D. R., Franks A. L., Atrash H. K., Pokras R. Epidemiology of preeclampsia and eclampsia in the United States, 1979-1986. Am J Obstet Gynecol. 1990 Aug;163(2):460–465. doi: 10.1016/0002-9378(90)91176-d. [DOI] [PubMed] [Google Scholar]
  15. Stockbauer J. W., Land G. H. Changes in characteristics of women who smoke during pregnancy: Missouri, 1978-88. Public Health Rep. 1991 Jan-Feb;106(1):52–58. [PMC free article] [PubMed] [Google Scholar]

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