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. 1993 May;83(5):743–745. doi: 10.2105/ajph.83.5.743

Hip fracture incidence before and after the fluoridation of the public water supply, Rochester, Minnesota.

S J Jacobsen 1, W M O'Fallon 1, L J Melton 3rd 1
PMCID: PMC1694705  PMID: 8484462

Abstract

Recent ecological comparison studies have suggested a positive association between fluoridation and hip fracture. Using data from the Rochester Epidemiology Project, we found the incidence of hip fracture for the 10 years before the fluoridation of the Rochester, Minn, public water supply was 484 per 100,000, compared with 450 per 100,000 in the following 10 years. When the effects of calendar time and age were controlled for, the relative risk associated with fluoridation was 0.63. These ecologic trend data suggest that the fluoridation of public water supplies is not associated with an immediate increase in rates of hip fracture. Further studies of this association at the individual level are clearly required before public policy decisions can be made.

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Selected References

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  1. Alffram P. A., Hernborg J., Nilsson B. E. The influence of a high fluoride content in the drinking water on the bone mineral mass in man. Acta Orthop Scand. 1969;40(2):137–142. doi: 10.3109/17453676908989494. [DOI] [PubMed] [Google Scholar]
  2. Arnala I., Alhava E. M., Kivivuori R., Kauranen P. Hip fracture incidence not affected by fluoridation. Osteofluorosis studied in Finland. Acta Orthop Scand. 1986 Aug;57(4):344–348. doi: 10.3109/17453678608994408. [DOI] [PubMed] [Google Scholar]
  3. Arnala I. Fluoridation and hip fractures. Med J Aust. 1987 Apr 20;146(8):451–451. doi: 10.5694/j.1326-5377.1987.tb120345.x. [DOI] [PubMed] [Google Scholar]
  4. Bernstein D. S., Sadowsky N., Hegsted D. M., Guri C. D., Stare F. J. Prevalence of osteoporosis in high- and low-fluoride areas in North Dakota. JAMA. 1966 Oct 31;198(5):499–504. [PubMed] [Google Scholar]
  5. Cooper C., Wickham C. A., Barker D. J., Jacobsen S. J. Water fluoridation and hip fracture. JAMA. 1991 Jul 24;266(4):513–514. [PubMed] [Google Scholar]
  6. Danielson C., Lyon J. L., Egger M., Goodenough G. K. Hip fractures and fluoridation in Utah's elderly population. JAMA. 1992 Aug 12;268(6):746–748. [PubMed] [Google Scholar]
  7. Goggin J. E., Haddon W., Jr, Hambly G. S., Hoveland J. R. Incidence of femoral fractures in postmenopausal women. Before and after water fluoridation. Public Health Rep. 1965 Nov;80(11):1005–1012. [PMC free article] [PubMed] [Google Scholar]
  8. Jacobsen S. J., Goldberg J., Cooper C., Lockwood S. A. The association between water fluoridation and hip fracture among white women and men aged 65 years and older. A national ecologic study. Ann Epidemiol. 1992 Sep;2(5):617–626. doi: 10.1016/1047-2797(92)90006-c. [DOI] [PubMed] [Google Scholar]
  9. Jacobsen S. J., Goldberg J., Miles T. P., Brody J. A., Stiers W., Rimm A. A. Hip fracture incidence among the old and very old: a population-based study of 745,435 cases. Am J Public Health. 1990 Jul;80(7):871–873. doi: 10.2105/ajph.80.7.871. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Jacobsen S. J., Goldberg J., Miles T. P., Brody J. A., Stiers W., Rimm A. A. Regional variation in the incidence of hip fracture. US white women aged 65 years and older. JAMA. 1990 Jul 25;264(4):500–502. [PubMed] [Google Scholar]
  11. Kurland L. T., Molgaard C. A. The patient record in epidemiology. Sci Am. 1981 Oct;245(4):54–63. doi: 10.1038/scientificamerican1081-54. [DOI] [PubMed] [Google Scholar]
  12. LEONE N. C. The effects of the absorption of fluoride. I. Outline and summary. AMA Arch Ind Health. 1960 Apr;21:324–325. [PubMed] [Google Scholar]
  13. Madans J., Kleinman J. C., Cornoni-Huntley J. The relationship between hip fracture and water fluoridation: an analysis of national data. Am J Public Health. 1983 Mar;73(3):296–298. doi: 10.2105/ajph.73.3.296. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Melton L. J., 3rd Fluoride in the prevention of osteoporosis and fractures. J Bone Miner Res. 1990 Mar;5 (Suppl 1):S163–S167. doi: 10.1002/jbmr.5650051352. [DOI] [PubMed] [Google Scholar]
  15. Melton L. J., 3rd, Ilstrup D. M., Riggs B. L., Beckenbaugh R. D. Fifty-year trend in hip fracture incidence. Clin Orthop Relat Res. 1982 Jan-Feb;(162):144–149. [PubMed] [Google Scholar]
  16. Melton L. J., 3rd, O'Fallon W. M., Riggs B. L. Secular trends in the incidence of hip fractures. Calcif Tissue Int. 1987 Aug;41(2):57–64. doi: 10.1007/BF02555245. [DOI] [PubMed] [Google Scholar]
  17. Riggs B. L., Hodgson S. F., O'Fallon W. M., Chao E. Y., Wahner H. W., Muhs J. M., Cedel S. L., Melton L. J., 3rd Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis. N Engl J Med. 1990 Mar 22;322(12):802–809. doi: 10.1056/NEJM199003223221203. [DOI] [PubMed] [Google Scholar]
  18. Simonen O., Laitinen O. Does fluoridation of drinking-water prevent bone fragility and osteoporosis? Lancet. 1985 Aug 24;2(8452):432–434. doi: 10.1016/s0140-6736(85)92748-5. [DOI] [PubMed] [Google Scholar]
  19. Sowers M. F., Clark M. K., Jannausch M. L., Wallace R. B. A prospective study of bone mineral content and fracture in communities with differential fluoride exposure. Am J Epidemiol. 1991 Apr 1;133(7):649–660. doi: 10.1093/oxfordjournals.aje.a115940. [DOI] [PubMed] [Google Scholar]
  20. Sowers M. R., Wallace R. B., Lemke J. H. The relationship of bone mass and fracture history to fluoride and calcium intake: a study of three communities. Am J Clin Nutr. 1986 Dec;44(6):889–898. doi: 10.1093/ajcn/44.6.889. [DOI] [PubMed] [Google Scholar]

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