Skip to main content
NCBI home page
British Medical Journal logoLink to British Medical Journal
. 1970 Jan 10;1(5688):74–75. doi: 10.1136/bmj.1.5688.74

Fibrin Degradation Products in Sera of Women with Normal Menstruation and Menorrhagia

Himansu K Basu
PMCID: PMC1699183  PMID: 5411448

Abstract

Serum concentrations of fibrin degradation products were found to be higher during menstruation than in the intermenstrual phase. Higher concentrations were present in cases of menorrhagia as compared with healthy women and women with various gynaecological disorders but with normal menstrual function. Higher serum concentrations of fibrin degradation products in cases of menorrhagia may indicate increased local fibrinolytic activity in the uterus.

Full text

PDF
74

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CLARKE R. L., CLIFFTON E. E. Oxygen saturation and spontaneous fibrinolytic activity. Am J Med Sci. 1962 Oct;244:466–471. [PubMed] [Google Scholar]
  2. Das P. C., Allan A. G., Woodfield D. G., Cash J. D. Fibrin degradation products in sera of normal subjects. Br Med J. 1967 Dec 23;4(5581):718–720. doi: 10.1136/bmj.4.5581.718. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Mackay A. V., Das P. C., Myerscough P. R., Cash J. D. Fibrinolytic components of human uterine arterial and venous blood. J Clin Pathol. 1967 May;20(3):227–230. doi: 10.1136/jcp.20.3.227. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Merskey C., Kleiner G. J., Johnson A. J. Quantitative estimation of split products of fibrinogen in human serum, relation to diagnosis and treatment. Blood. 1966 Jul;28(1):1–18. [PubMed] [Google Scholar]
  5. NILSSON I. M., BJOERKMAN S. E. EXPERIENCES WITH EPSILON-AMINOCAPROIC ACID (EPSILON-ACA) IN THE TREATMENT OF PROFUSE MENSTRUATION. Acta Med Scand. 1965 Apr;177:445–457. [PubMed] [Google Scholar]
  6. Nilsson L., Rybo G. Treatment of menorrhagia with epsilon aminocaproic acid. A double blind investigation. Acta Obstet Gynecol Scand. 1965;44(3):467–473. doi: 10.3109/00016346509155880. [DOI] [PubMed] [Google Scholar]
  7. Prentice C. R., McNicol G. P., Douglas A. S. Plasminogen activation and the coagulation process. J Clin Pathol. 1969 May;22(3):367–368. doi: 10.1136/jcp.22.3.367. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. RATNOFF O. D., MENZIE C. A new method for the determination of fibrinogen in small samples of plasma. J Lab Clin Med. 1951 Feb;37(2):316–320. [PubMed] [Google Scholar]
  9. RUMBOLZ W. L., MOON C. F., NOVELLI J. C. Use of protamine sulfate and toluidine blue for abnormal uterine bleeding. Am J Obstet Gynecol. 1952 May;63(5):1029–1037. doi: 10.1016/0002-9378(52)90542-5. [DOI] [PubMed] [Google Scholar]
  10. Rybo G. Plasminogen activators in the endometrium. II. Clinical aspects. Variation in the concentration of plasminogen activators during the menstrual cycle and its relation to menstrual blood loss. Acta Obstet Gynecol Scand. 1966;45(4):429–450. doi: 10.3109/00016346609158462. [DOI] [PubMed] [Google Scholar]
  11. Salvatore C. A. Identification of fibrin in menstrual endometrium. Am J Obstet Gynecol. 1969 Feb 15;103(4):537–543. doi: 10.1016/s0002-9378(15)31856-1. [DOI] [PubMed] [Google Scholar]
  12. Vermylen J., Verhaegen-Declercq M. L., Verstraete M., Fierens F. A double blind study of the effect of tranexamic acid in essential menorrhagia. Thromb Diath Haemorrh. 1968 Dec 31;20(3):583–587. [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES