Abstract
Experience with dextro-alprenolol in nine patients has shown that it is relatively ineffective in treating arrhythmias associated with acute myocardial infarction. Marginal effectiveness in the control of ventricular ectopic beats after myocardial infarction is outweighed by an appreciable hypotensive effect with risk of infarction. The drug was ineffective in the management of supraventricular arrhythmias.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Epstein S. E., Braunwald E. Beta-adrenergic receptor blocking drugs. Mechanisms of action and clinical applications. N Engl J Med. 1966 Nov 17;275(20):1106–contd. doi: 10.1056/NEJM196611172752006. [DOI] [PubMed] [Google Scholar]
- Linko E., Ruosteenoja R., Siitonen L. A clinical study on the mechanism of the antiarrhythmic action of a new antagonist to beta-adrenergic receptor. Am Heart J. 1968 Jan;75(1):139–140. doi: 10.1016/0002-8703(68)90125-7. [DOI] [PubMed] [Google Scholar]
- Lord C. O., Katz R. L., Eakins K. E. Antiarrhythmic properties of stereoisomers of a beta-adrenergic blocking agent (H56-28). Anesthesiology. 1968 Mar-Apr;29(2):288–294. doi: 10.1097/00000542-196803000-00011. [DOI] [PubMed] [Google Scholar]
- Sloman G., Stannard M. Beta-adrenergic blockade and cardiac arrhythmias. Br Med J. 1967 Dec 2;4(5578):508–512. doi: 10.1136/bmj.4.5578.508. [DOI] [PMC free article] [PubMed] [Google Scholar]
