Abstract
Nifuratel (Magmilor) was compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis by a randomized double-blind trial. Only 18 out of 47 patients (38%) treated with nifuratel were found to be cured, whereas 42 out of 49 patients (85%) treated with metronidazole were cured. Severe reactions, necessitating withdrawal of treatment, occurred in three patients treated with nifuratel. There were no serious side-effects with metronidazole. The results of this trial indicate that nifuratel is not a satisfactory substitute for metronidazole in the treatment of trichomoniasis.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Arnold M., Delnon J. Die Behandlung des Fluor vaginalis mit Macmiror. Ther Umsch. 1965 Oct;22(10):490–497. [PubMed] [Google Scholar]
- Churcher G. M., Evans A. J. Inhibition of Neisseria gonorrhoeae by nifuratel. Br J Vener Dis. 1969 Jun;45(2):149–150. doi: 10.1136/sti.45.2.149. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DUREL P., ROIRON V., SIBOULET A., BOREL L. J. Essai d'un antitrichomonas dérivé de l'imidazole: 8823 R.P. C R Soc Fr Gyncol. 1959 Jan;29(1):36–45. [PubMed] [Google Scholar]
- DUREL P., ROIRON V., SIBOULET A., BOREL L. J. Systemic treatment of human trichomoniasis with a derivative of nitro-imidazole, 8823 RP. Br J Vener Dis. 1960 Mar;36:21–26. doi: 10.1136/sti.36.1.21. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fowler W., Hussain M. Nifuratel (Magmilor) in trichomonal vaginitis. Br J Vener Dis. 1968 Dec;44(4):331–333. doi: 10.1136/sti.44.4.331. [DOI] [PMC free article] [PubMed] [Google Scholar]
- RODIN P., KING A. J., NICOL C. S., BARROW J. Flagyl in the treatment of trichomoniasis. Br J Vener Dis. 1960 Sep;36:147–151. doi: 10.1136/sti.36.3.147. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Struthers J. O. The treatment of vaginal infection with nifuratel. Br J Clin Pract. 1969 Oct;23(10):417–419. [PubMed] [Google Scholar]