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. 1976 Sep;32(3):324–326. doi: 10.1128/aem.32.3.324-326.1976

Inhibition of aflatoxin formation by 2-mercaptoethanol.

S K Gupta, K K Maggon, T A Venkitasubramanian
PMCID: PMC170064  PMID: 984814

Abstract

2-Mercaptoethanol inhibits growth of Aspergillus parasiticus NRRL 3240 and aflatoxin formation by the fungus. When added to the resuspended medium, 2-mercaptoethanol inhibited [1-14C]acetate incorporation into both aflatoxins and neutral lipids, thereby showing that it acts at an early stage of aflatoxin biosynthesis. The inhibition is probably due to its chelating action on zinc, which is essential for aflatoxin production. It is proposed that any chelating agent that selectively binds to zinc will inhibit aflatoxin formation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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